SCHEMBL21472980

SCHEMBL21472980

c1ccc(-c2ccc3c(c2)c2ccc4c5ccccc5c5cccc6c5c4c2n36)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 3/20 0.38
MAOB P27338 1/20 0.33
DNM1 Q05193 1/20 0.33
SRC P12931 1/20 0.33
PRKACA P17612 1/20 0.33
PRKACG P22612 1/20 0.33
PRKACB P22694 1/20 0.33
NR4A2 P43354 2/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
PLA2G2A P14555 2/20 0.32
PLA2G4A P47712 2/20 0.32
LIMK1 P53667 1/20 0.32
NPY5R Q15761 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
NR3C1 P04150 1/20 0.31
PLA2G10 O15496 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21472981 1.00 TSPO (0.38) TSPOMAOBDNM1SRCPRKACA
SCHEMBL21473028 0.94 TSPO (0.32) TSPOKDM4EMEN1ALDH1A1MAPT
SCHEMBL21472982 0.92 TSPO (0.34) TSPOSRCPRKACAPRKACGPRKACB
SCHEMBL21473077 0.91 KDM4E (0.34) TSPONR3C1KDM4E
SCHEMBL21472984 0.88 MEN1 (0.34) NPY5RCYP3A4CYP2C9KDM4EMEN1
SCHEMBL21473103 0.88 KDM4E (0.39) TSPOKDM4E
SCHEMBL21473042 0.88 L3MBTL1 (0.46) TSPOKDM4EMEN1ALDH1A1MAPT
SCHEMBL19978087 0.88 TSPO (0.40) TSPOMAOBSRCPRKACAPRKACG
SCHEMBL21472983 0.87 HSD17B1 (0.40) CYP3A4CYP2C9HSD17B1HSD17B2KDM4E
SCHEMBL23776037 0.86 TSPO (0.38) TSPOMAOBDNM1SRCPRKACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES OSBP, OSBP2, OSBPL3 TSPO 2875/4885MAOB 319/4885DNM1 629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.