SCHEMBL21473097

SCHEMBL21473097

c1ccc(-c2ccc(-c3cc4c5ccccc5n5c6cccc7c8ccccc8c3c(c76)c45)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.34
POLB P06746 1/20 0.32
KDM4E B2RXH2 2/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
PLEC Q15149 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TSHR P16473 1/20 0.30
HTR6 P50406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21473078 0.97 HSD17B10 (0.36) HSD17B10POLBKDM4EMEN1MAPT
SCHEMBL21473023 0.91 MEN1 (0.33) HSD17B10POLBKDM4EMEN1MAPT
SCHEMBL21473922 0.88 POLB (0.30) POLB
SCHEMBL21461879 0.86 HSD17B10 (0.37) HSD17B10KDM4EMEN1MAPTRECQL
SCHEMBL21473022 0.85 GSTP1 (0.37) HSD17B10KDM4E
SCHEMBL21473111 0.83 KDM4E (0.43) KDM4EKMT2A
SCHEMBL20444570 0.82 TSPO (0.39) HSD17B10KDM4EMEN1MAPTRECQL
SCHEMBL21473110 0.81 ALOX5 (0.34) MAPT
SCHEMBL21473020 0.80 HSD17B10 (0.39) HSD17B10POLBKDM4EKMT2ATSHR
SCHEMBL21472957 0.80 PSEN1 (0.32) HSD17B10KDM4EMEN1MAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES OSBP, OSBP2, OSBPL3 HSD17B10 804/4885POLB 1890/4885KDM4E 4292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.