Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21465468 | 0.93 | ABCB11 (0.51) | ABCB11PTGS2CCR2MEN1CYP3A4 | |
| SCHEMBL23759961 | 0.93 | ABCB11 (0.55) | ABCB11PTGS2CCR2MEN1CYP3A4 | |
| SCHEMBL21465538 | 0.89 | PTGS2 (0.49) | PTGS2CCR2MEN1CYP3A4MAPT | |
| SCHEMBL21465503 | 0.89 | ABCB11 (0.51) | ABCB11PTGS2CCR2MEN1CYP3A4 | |
| SCHEMBL21465479 | 0.88 | ABCB11 (0.67) | ABCB11CCR2MEN1CYP3A4MAPT | |
| SCHEMBL21465625 | 0.87 | PTGES2 (0.48) | PTGS2CCR2MEN1CYP3A4MAPT | |
| SCHEMBL21465506 | 0.87 | PTGS2 (0.47) | PTGS2MEN1CYP3A4MAPTTSHR | |
| SCHEMBL21465556 | 0.86 | PLA2G2A (0.53) | ABCB11CCR2MEN1CYP3A4MAPT | |
| SCHEMBL25761979 | 0.85 | MEN1 (0.52) | ABCB11PTGS2CCR2MEN1CYP3A4 | |
| SCHEMBL21465632 | 0.84 | PTGDR2 (0.51) | ABCB11PTGS2CCR2MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11690824-B2 | Antibacterial compounds | THE GENERAL HOSPITAL CORPORATION (US) | 2023-07-04 | — | — | US | disclosed |
| US-11690824-B2 | Antibacterial compounds | THE GENERAL HOSPITAL CORPORATION (US) | 2023-07-04 | — | — | US | disclosed |
| US-11690824-B2 | Antibacterial compounds | THE GENERAL HOSPITAL CORPORATION (US) | 2023-07-04 | — | — | US | disclosed |
| US-20210251958-A1 | Antibacterial Compounds | RHODE ISLAND HOSPITAL, A LIFESPAN-PARTNER | 2021-08-19 | — | — | US | disclosed |
| US-20210251958-A1 | Antibacterial Compounds | RHODE ISLAND HOSPITAL, A LIFESPAN-PARTNER | 2021-08-19 | — | — | US | disclosed |
| WO-2019199979-A1 | ANTIBACTERIAL COMPOUNDS | THE GENERAL HOSPITAL CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11690824-B2 | Antibacterial compounds | MRPL21, SPOUT1, BAX | ABCB11 280/4885PTGS2 446/4885CCR2 3443/4885 |
| US-20210251958-A1 | Antibacterial Compounds | MRPL21, SPOUT1, BAX | ABCB11 280/4885PTGS2 446/4885CCR2 3443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.