Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20234383 | 0.76 | MEP1B (0.46) | CYP4A11CYP4F2MEP1B | |
| SCHEMBL21468519 | 0.75 | KMT2A (0.39) | METAP2MEP1BMEN1GFERKMT2A | |
| SCHEMBL21468485 | 0.74 | CYP2C9 (0.34) | METAP2MEN1GFERKMT2ASMN1; SMN2 | |
| SCHEMBL24362372 | 0.69 | MEP1B (0.48) | MEP1BSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL30548827 | 0.69 | MEP1B (0.48) | MEP1BSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL20234381 | 0.68 | MEP1B (0.50) | MEP1BMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL19234390 | 0.67 | GABRA1 (0.41) | CYP4A11CYP4F2PPARA | |
| SCHEMBL21468471 | 0.66 | RAB9A (0.43) | CYP4A11CYP4F2PPARARAB9A | |
| SCHEMBL31616466 | 0.66 | CYP4F2 (0.38) | CYP4A11CYP4F2CYP2C9LMNAPGR | |
| SCHEMBL28111049 | 0.65 | CYP4F2 (0.36) | CYP4A11CYP4F2CYP2C9LMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450263-B2 | Benzo annulenes as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450263-B2 | Benzo annulenes as antiviral agents | MAVS, ZC3HAV1, GABBR1 | METAP2 3878/4885CYP4A11 3508/4885CYP4F2 3688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.