SCHEMBL21470104

SCHEMBL21470104

BNC(=O)C(=C)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.32
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10005742 0.74 CA2 (0.32) CA2TGM2
SCHEMBL20100393 0.72 CA2 (0.42) CA2
SCHEMBL9004537 0.70 TGM2 (0.38) TGM2
SCHEMBL12057427 0.70 KDM4E (0.32)
SCHEMBL6886083 0.69 MMP1 (0.38) TGM2
SCHEMBL25762120 0.69 MLYCD (0.40) CA2
SCHEMBL973725 0.67 CA2 (0.33) CA2
SCHEMBL20100302 0.67 CYP1A2 (0.38) CA2
SCHEMBL15226520 0.67 EGLN1 (0.43) TGM2
SCHEMBL31602228 0.67 CA1 (0.41) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019196714-A1 N-SUBSTITUTED ACRYLAMIDE DERIVATIVE AS DHODH INHIBITOR, AND PREPARATION AND USE THEREOF 华东理工大学 2019-10-17 WO disclosed