Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 15/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21470702 | 0.92 | GHSR (0.33) | GHSRNPC1POLBKDM4EPARP1 | |
| SCHEMBL21470768 | 0.86 | GHSR (0.36) | GHSRNPC1POLBKDM4E | |
| SCHEMBL21470771 | 0.84 | GHSR (0.37) | GHSRNPC1POLBPARP1 | |
| SCHEMBL23353650 | 0.79 | GHSR (0.36) | GHSRNPC1POLBPARP1 | |
| SCHEMBL21470766 | 0.78 | HTR6 (0.39) | GHSRHDAC8 | |
| SCHEMBL21470704 | 0.77 | GHSR (0.37) | GHSRPARP1 | |
| SCHEMBL21470487 | 0.76 | GHSR (0.36) | GHSRPARP1 | |
| SCHEMBL23353525 | 0.76 | GHSR (0.38) | GHSRHDAC8PARP1 | |
| SCHEMBL23327005 | 0.74 | TAS2R14 (0.35) | NPC1POLBKDM4EPARP1 | |
| SCHEMBL21470700 | 0.73 | GHSR (0.36) | GHSRPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019200120-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | LYCERA CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |