Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 16/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21470700 | 0.92 | GHSR (0.36) | GHSRPARP1TAS2R14HTR6 | |
| SCHEMBL21470704 | 0.90 | GHSR (0.37) | GHSRPARP1TAS2R14 | |
| SCHEMBL21470487 | 0.89 | GHSR (0.36) | GHSRPARP1TAS2R14HTR6 | |
| SCHEMBL21470771 | 0.89 | GHSR (0.37) | GHSRPARP1TAS2R14HTR6 | |
| SCHEMBL23353650 | 0.88 | GHSR (0.36) | GHSRPARP1TAS2R14 | |
| SCHEMBL21470766 | 0.85 | HTR6 (0.39) | GHSRTAS2R14HDAC8HTR6 | |
| SCHEMBL23326996 | 0.81 | TAS2R14 (0.36) | PARP1TAS2R14 | |
| SCHEMBL23327045 | 0.80 | TAS2R14 (0.35) | PARP1TAS2R14HTR6 | |
| SCHEMBL23327005 | 0.80 | TAS2R14 (0.35) | PARP1TAS2R14 | |
| SCHEMBL23326956 | 0.77 | TAS2R14 (0.35) | PARP1TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139484-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | GOSSAMER BIO SERVICES INC (US) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139484-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ULK1, PHKG2, PHKG1 | GHSR 2448/4885PARP1 227/4885TAS2R14 4112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.