Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.32 |
| ▸ | RELA | Q04206 | 4/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20276637 | 0.87 | KMT2A (0.39) | SYKSERPINE1AAK1L3MBTL1KMT2A | |
| SCHEMBL16654975 | 0.83 | AKT1 (0.37) | AKT1SYKSERPINE1L3MBTL1KMT2A | |
| SCHEMBL16654977 | 0.83 | AKT1 (0.37) | AKT1SYKSERPINE1L3MBTL1KMT2A | |
| SCHEMBL24978375 | 0.83 | AKT1 (0.37) | AKT1SYKSERPINE1L3MBTL1KMT2A | |
| SCHEMBL31004974 | 0.82 | AKT1 (0.45) | AKT1KMT2AGAAMEN1NFKB1 | |
| SCHEMBL11632667 | 0.81 | L3MBTL1 (0.38) | SYKSERPINE1L3MBTL1KMT2AGAA | |
| SCHEMBL11632674 | 0.81 | L3MBTL1 (0.38) | SYKSERPINE1L3MBTL1KMT2AGAA | |
| SCHEMBL6798906 | 0.78 | L3MBTL1 (0.38) | SYKSERPINE1AAK1L3MBTL1KMT2A | |
| SCHEMBL5257223 | 0.78 | L3MBTL1 (0.38) | SYKSERPINE1AAK1L3MBTL1KMT2A | |
| SCHEMBL880771 | 0.76 | KMT2A (0.37) | SYKSERPINE1AAK1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190314519-A1 | TARGETED DELIVERY OF NICOTINAMIDE ADENINE DINUCLEOTIDE SALVAGE PATHWAY INHIBITORS | SEATTLE GENETICS, INC. (US) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190314519-A1 | TARGETED DELIVERY OF NICOTINAMIDE ADENINE DINUCLEOTIDE SALVAGE PATHWAY INHIBITORS | NAMPT, NME4, NNMT | AKT1 327/4885SYK 3131/4885SERPINE1 1360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.