Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924804 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TSHRGPR35SMN1; SMN2TP53 | |
| SCHEMBL7296254 | 0.81 | GPR35 (0.50) | ALDH1A1TSHRGPR35SMN1; SMN2TP53 | |
| SCHEMBL31493924 | 0.79 | HTT (0.66) | ALDH1A1TSHRGPR35SMN1; SMN2TP53 | |
| SCHEMBL221924 | 0.79 | HTT (0.66) | ALDH1A1TSHRGPR35SMN1; SMN2TP53 | |
| SCHEMBL8588024 | 0.78 | HTT (0.60) | ALDH1A1SMN1; SMN2HPGDMAPK1HTT | |
| Potassium Ion SCHEMBL1531373 | 0.77 | HTT (0.64) | ALDH1A1TSHRGPR35SMN1; SMN2TP53 | |
| SCHEMBL22534526 | 0.77 | HTT (0.64) | ALDH1A1TSHRGPR35SMN1; SMN2TP53 | |
| SCHEMBL31296069 | 0.77 | HTT (0.64) | ALDH1A1TSHRGPR35SMN1; SMN2TP53 | |
| Ammonia Solution, Strong SCHEMBL28302337 | 0.77 | HTT (0.64) | ALDH1A1TSHRGPR35SMN1; SMN2TP53 | |
| SCHEMBL1531372 | 0.77 | HTT (0.64) | ALDH1A1TSHRGPR35SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2710380-B1 | METHOD OF DETECTION OF AMINO ACID SEQUENCE AND/OR IDENTIFICATION OF PEPTIDES AND PROTEINS, BY USE OF A NEW DERIVATIZATION REAGENT AND SYNTHESIS OF 5-FORMYL-BENZENE-1,3-DISULPHONIC ACID AS DERIVATIZATION REAGENT | RUDJER BOSKOVIC INST (HR) | 2017-06-28 | — | — | EP | disclosed |
| US-9581601-B2 | Method of detection of amino acid sequence and/or identification of peptides and proteins, by use of a new derivatization reagent and synthesis of 5-formyl-benzene-1,3-disulphonic acid as derivatization reagent | RUDJER BOSKOVIC INSTITUTE (HR) | 2017-02-28 | — | — | US | disclosed |
| US-20150233937-A1 | METHOD OF DETECTION OF AMINO ACID SEQUENCE AND/OR IDENTIFICATION OF PEPTIDES AND PROTEINS, BY USE OF A NEW DERIVATIZATION REAGENT AND SYNTHESIS OF 5-FORMYL-BENZENE-1,3-DISULPHONIC ACID AS DERIVATIZATION REAGENT | RUDJER BOSKOVIC INSTITUTE (HR) | 2015-08-20 | — | — | US | disclosed |
| EP-2710380-A1 | METHOD OF DETECTION OF AMINO ACID SEQUENCE AND/OR IDENTIFICATION OF PEPTIDES AND PROTEINS, BY USE OF A NEW DERIVATIZATION REAGENT AND SYNTHESIS OF 5-FORMYL-BENZENE-1,3-DISULPHONIC ACID AS DERIVATIZATION REAGENT | Rudjer Boskovic Institute (HR) | 2014-03-26 | — | — | EP | disclosed |
| US-8647880-B2 | Mass spectrometry-based protein identification method with selective N-terminus derivatization | Rudjer Bosckovic Institute (HR) | 2014-02-11 | — | — | US | disclosed |
| EP-2529233-B1 | MASS SPECTROMETRY-BASED PROTEIN IDENTIFICATION | RUDJER BOSKOVIC INST (HR) | 2013-10-23 | — | — | EP | disclosed |
| EP-2529233-A2 | MASS SPECTROMETRY-BASED PROTEIN IDENTIFICATION | Rudjer Boskovic Institute (HR) | 2012-12-05 | — | — | EP | disclosed |
| WO-2012156764-A1 | METHOD OF DETECTION OF AMINO ACID SEQUENCE AND/OR IDENTIFICATION OF PEPTIDES AND PROTEINS, BY USE OF A NEW DERIVATIZATION REAGENT AND SYNTHESIS OF 5-FORMYL-BENZENE-1,3-DISULPHONIC ACID AS DERIVATIZATION REAGENT | RUDJER BOSKOVIC INSTITUTE (HR) | 2012-11-22 | — | — | WO | disclosed |
| US-20110212531-A1 | Mass Spectrometry-Based Protein Identification Method | RUDJER BOSKOVIC INSTITUTE (HR) | 2011-09-01 | — | — | US | disclosed |
| WO-2011089453-A2 | MASS SPECTROMETRY-BASED PROTEIN IDENTIFICATION | RUDJER BOSKOVIC INSTITUTE (HR) | 2011-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150233937-A1 | METHOD OF DETECTION OF AMINO ACID SEQUENCE AND/OR IDENTIFICATION OF PEPTIDES AND PROTEINS, BY USE OF A NEW DERIVATIZATION REAGENT AND SYNTHESIS OF 5-FORMYL-BENZENE-1,3-DISULPHONIC ACID AS DERIVATIZATION REAGENT | PTMS, FABP5, FPR1 | ALDH1A1 3275/4885TSHR 2840/4885GPR35 1621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.