Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | SYK | P43405 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21473789 | 0.93 | L3MBTL1 (0.57) | L3MBTL1NPSR1KEAP1NFE2L2ALDH1A1 | |
| Toluene SCHEMBL28430347 | 0.86 | L3MBTL1 (0.54) | L3MBTL1NPSR1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL2760129 | 0.84 | L3MBTL1 (0.65) | L3MBTL1NPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL18557437 | 0.84 | L3MBTL1 (0.56) | L3MBTL1NPSR1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL64435 | 0.83 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29373231 | 0.83 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7355640 | 0.82 | NPSR1 (0.64) | L3MBTL1NPSR1ALDH1A1SYKHRH3 | |
| Hydrochloric Acid SCHEMBL31087535 | 0.81 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1NPC1RAB9AHRH3 | |
| SCHEMBL31276017 | 0.81 | L3MBTL1 (0.66) | L3MBTL1ALDH1A1NPC1RAB9AHRH3 | |
| Bromide SCHEMBL10759788 | 0.81 | L3MBTL1 (0.66) | L3MBTL1ALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106032355-B | A kind of method that pyridine side chain c h bond is direct oxidation into ketone | 中国科学院大连化学物理研究所 | 2019-01-04 | — | — | CN | claimed |
| CN-106032355-A | Method for directly oxidizing C-H bond in side chain of pyridine into ketone | 中国科学院大连化学物理研究所 | 2016-10-19 | — | — | CN | claimed |
| EP-3511294-B1 | METHOD FOR STORING AND DISCHARGING HYDROGEN USING PYRIDINE-BASED HYDROGEN STORAGE MATERIAL | KOREA RES INST CHEMICAL TECH (KR) | 2022-06-15 | — | — | EP | disclosed |
| CN-112661696-A | Green synthesis method of multi-aryl substituted methanol | 华东理工大学 | 2021-04-16 | — | — | CN | disclosed |
| US-10693083-B2 | Condensed cyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2020-06-23 | — | — | US | disclosed |
| EP-3511294-A1 | SYSTEM FOR STORING AND DISCHARGING HYDROGEN USING PYRIDINE-BASED HYDROGEN STORAGE MATERIAL | Korea Research Institute of Chemical Technology (KR) | 2019-07-17 | — | — | EP | disclosed |
| US-10355284-B2 | Composition, method of preparing the composition, electrode including the composition, and fuel cell including the electrode | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2019-07-16 | — | — | US | disclosed |
| US-10276799-B2 | White-light hyperbranched conjugated polymer, method for preparing the same and it's use | TAIYUAN UNIVERSITY OF TECHNOLOGY (CN) | 2019-04-30 | — | — | US | disclosed |
| CN-106032355-B | A kind of method that pyridine side chain c h bond is direct oxidation into ketone | 中国科学院大连化学物理研究所 | 2019-01-04 | — | — | CN | disclosed |
| US-20180166635-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-06-14 | — | — | US | disclosed |
| CN-105669548-B | A kind of method of manganese compound catalysis oxidation pyridine compounds and their synthesis ketone | 中国科学院大连化学物理研究所 | 2018-04-03 | — | — | CN | disclosed |
| US-7517880-B2 | Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-04-14 | — | — | US | disclosed |
| US-7517880-B2 | Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-04-14 | — | — | US | disclosed |
| US-20090093526-A1 | INHIBITION OF P38 KINASE USING SYMMETRICAL AND UNSYMMETRICAL DIPHENYL UREAS | BAYER HEALTHCARE LLC | 2009-04-09 | — | — | US | disclosed |
| US-20090093526-A1 | INHIBITION OF P38 KINASE USING SYMMETRICAL AND UNSYMMETRICAL DIPHENYL UREAS | BAYER HEALTHCARE LLC | 2009-04-09 | — | — | US | disclosed |
| US-20080269265-A1 | Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas | MILLER SCOTT | 2008-10-30 | — | — | US | disclosed |
| US-20080269265-A1 | Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas | MILLER SCOTT | 2008-10-30 | — | — | US | disclosed |
| CN-101128421-A | Methods and compositions for treating amyloid-related diseases | NEUROCHEM INTERNAT LTD (CH) | 2008-02-20 | — | — | CN | disclosed |
| US-20070244120-A1 | INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS | BAYER HEALTHCARE LLC | 2007-10-18 | — | — | US | disclosed |
| US-20070244120-A1 | INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS | BAYER HEALTHCARE LLC | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093526-A1 | INHIBITION OF P38 KINASE USING SYMMETRICAL AND UNSYMMETRICAL DIPHENYL UREAS | MAP2K2, MAPK1, MAP2K1 | L3MBTL1 2701/4885NPSR1 4077/4885KEAP1 2179/4885 |
| US-20180166635-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CRY1, CRY2, CCNE2 | L3MBTL1 1898/4885NPSR1 4281/4885KEAP1 302/4885 |
| US-20070244120-A1 | INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS | BRAF, RAF1, ARAF | L3MBTL1 1879/4885NPSR1 4583/4885KEAP1 782/4885 |
| US-10693083-B2 | Condensed cyclic compound and organic light-emitting device including the same | CRY1, CRY2, CCNE2 | L3MBTL1 1898/4885NPSR1 4281/4885KEAP1 302/4885 |
| US-20080269265-A1 | Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas | BRAF, RAF1, MAP2K2 | L3MBTL1 2090/4885NPSR1 4614/4885KEAP1 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.