Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28702125 | 0.77 | SLC1A2 (0.31) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3810813 | 0.77 | TDP1 (0.39) | TDP1 | |
| SCHEMBL25660318 | 0.76 | SLC1A2 (0.41) | CA2MAPK1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28654671 | 0.74 | ALDH1A1 (0.33) | TDP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3367991 | 0.74 | OR51E2 (0.31) | — | |
| SCHEMBL5682222 | 0.72 | GRIK1 (0.33) | — | |
| SCHEMBL3400402 | 0.72 | SLC1A2 (0.35) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7108725 | 0.72 | — | — | |
| SCHEMBL11401855 | 0.71 | FOLH1 (0.38) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10582999 | 0.71 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542531-B1 | PROCESS FOR SYNTHESIS OF FIPRONIL | GHARDA KEKI HORMUSJI (IN) | 2014-09-17 | — | — | EP | claimed |
| US-8507693-B2 | Process for synthesis of fipronil | Gharda Medical and Advanced Technologies Foundation (IN) | 2013-08-13 | — | — | US | claimed |
| US-20130030190-A1 | PROCESS FOR SYNTHESIS FIPRONIL | Gharda Medical and Advanced Technologies Foundation (IN) | 2013-01-31 | — | — | US | claimed |
| EP-2542531-A1 | PROCESS FOR SYNTHESIS OF FIPRONIL | Gharda, Keki Hormusji (IN) | 2013-01-09 | — | — | EP | claimed |
| CN-102781920-A | Process for synthesizing fipronil | HORMUSJI GHARDA KEKI | 2012-11-14 | — | — | CN | claimed |
| WO-2011107998-A1 | PROCESS FOR SYNTHESIS OF FIPRONIL | GHARDA KEKI HORMUSJI (IN) | 2011-09-09 | — | — | WO | claimed |
| EP-2702039-B1 | A PROCESS FOR PREPARATION OF DICYANOCARBOXYLATE DERIVATIVES | GHARDA KEKI HORMUSJI (IN) | 2017-12-20 | — | — | EP | disclosed |
| US-9309190-B2 | Process for preparation of dicyanocarboxylate derivatives | Gharda Medical and Advanced Technologies Foundation (IN) | 2016-04-12 | — | — | US | disclosed |
| CN-102781920-B | Process for synthesizing fipronil | KEKI HORMUSJI GHARDA | 2015-05-20 | — | — | CN | disclosed |
| EP-2542531-B1 | PROCESS FOR SYNTHESIS OF FIPRONIL | GHARDA KEKI HORMUSJI (IN) | 2014-09-17 | — | — | EP | disclosed |
| EP-2702039-A1 | A PROCESS FOR PREPARATION OF DICYANOCARBOXYLATE DERIVATIVES | Gharda, Keki Hormusji (IN) | 2014-03-05 | — | — | EP | disclosed |
| US-20140051881-A1 | PROCESS FOR PREPARATION OF DICYANOCARBOXYLATE DERIVATIVES | Gharda Medical and Advanced Technologies Foundation (IN) | 2014-02-20 | — | — | US | disclosed |
| US-8507693-B2 | Process for synthesis of fipronil | Gharda Medical and Advanced Technologies Foundation (IN) | 2013-08-13 | — | — | US | disclosed |
| WO-2012147093-A1 | A PROCESS FOR PREPARATION OF DICYANOCARBOXYLATE DERIVATIVES | GHARDA KEKI HORMUSJI (IN) | 2012-11-01 | — | — | WO | disclosed |
| WO-2011107998-A1 | PROCESS FOR SYNTHESIS OF FIPRONIL | GHARDA KEKI HORMUSJI (IN) | 2011-09-09 | — | — | WO | disclosed |
| WO-2011086570-A1 | PROCESS FOR PREPARATION OF CYANOALKYLPROPIONATE DERIVATIVES | GHARDA KEKI HORMUSJI (IN) | 2011-07-21 | — | — | WO | disclosed |
| EP-1773759-A1 | PROCESS FOR PREPARING SYNTHETIC INTERMEDIATES USEFUL IN PREPARING PYRAZOLE COMPOUNDS | Pfizer Limited (GB) | 2007-04-18 | — | — | EP | disclosed |
| CN-1785966-A | Technology of synthesizing 2,3-dicyano ethyl propionate | LUAN ZHONGYUE (CN) | 2006-06-14 | — | — | CN | disclosed |
| WO-2006003501-A1 | PROCESS FOR PREPARING SYNTHETIC INTERMEDIATES USEFUL IN PREPARING PYRAZOLE COMPOUNDS | PFIZER LIMITED (GB) | 2006-01-12 | — | — | WO | disclosed |
| EP-0295117-B1 | Derivative of a N-phenylpyrazole | RHONE POULENC AGRICULTURE (GB) | 2000-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130030190-A1 | PROCESS FOR SYNTHESIS FIPRONIL | FIP1L1, CYP2F1, PFAS | CA2 2859/4885MAPK1 2135/4885CHRM1 4097/4885 |
| US-20140051881-A1 | PROCESS FOR PREPARATION OF DICYANOCARBOXYLATE DERIVATIVES | CA2, PCCA, C9 | CA2 1/4885MAPK1 654/4885CHRM1 3398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.