Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27385781 | 0.86 | GABRA1 (0.44) | ALDH1A1KDM4EGAANPSR1HTT | |
| SCHEMBL6534944 | 0.83 | MAP2 (0.41) | ALDH1A1KDM4ENPSR1HTTGABRA1 | |
| SCHEMBL21465510 | 0.82 | KDM4E (0.60) | ALDH1A1KDM4EGAANPSR1HTT | |
| SCHEMBL21465541 | 0.82 | MAPT (0.57) | ALDH1A1KDM4EGAANPSR1HTT | |
| SCHEMBL21465529 | 0.82 | KMT2A (0.56) | ALDH1A1KDM4EGAANPSR1HTT | |
| SCHEMBL16651672 | 0.81 | MEN1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL30572914 | 0.78 | KDM4E (0.69) | ALDH1A1KDM4EGAANPSR1HTT | |
| SCHEMBL4207606 | 0.78 | KDM4E (0.69) | ALDH1A1KDM4EGAANPSR1HTT | |
| SCHEMBL1210328 | 0.75 | ALDH1A1 (0.52) | ALDH1A1KDM4EGAAGABRA1GABRG2 | |
| SCHEMBL10925064 | 0.73 | ICMT (0.50) | ALDH1A1KDM4EGAANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199979-A1 | ANTIBACTERIAL COMPOUNDS | THE GENERAL HOSPITAL CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |