Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.58 |
| ▸ | TUBB | P07437 | 5/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.58 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308065 | 0.84 | KDM4E (0.58) | KDM4EALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL25751659 | 0.84 | KDM4E (0.58) | KDM4EALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL21465557 | 0.84 | TUBB4A (0.65) | KDM4EALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL21465529 | 0.82 | KMT2A (0.56) | KDM4EALDH1A1HPGDNPSR1GAA | |
| SCHEMBL21474560 | 0.82 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL21465541 | 0.82 | MAPT (0.57) | KDM4EALDH1A1HPGDNPSR1GAA | |
| SCHEMBL6313673 | 0.81 | GSK3B (0.56) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3253095 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL5402454 | 0.81 | ALOX15 (0.60) | KDM4EALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL29953042 | 0.81 | ALOX15 (0.60) | KDM4EALDH1A1HPGDTUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11690824-B2 | Antibacterial compounds | THE GENERAL HOSPITAL CORPORATION (US) | 2023-07-04 | — | — | US | disclosed |
| US-11690824-B2 | Antibacterial compounds | THE GENERAL HOSPITAL CORPORATION (US) | 2023-07-04 | — | — | US | disclosed |
| US-11690824-B2 | Antibacterial compounds | THE GENERAL HOSPITAL CORPORATION (US) | 2023-07-04 | — | — | US | disclosed |
| US-20210251958-A1 | Antibacterial Compounds | RHODE ISLAND HOSPITAL, A LIFESPAN-PARTNER | 2021-08-19 | — | — | US | disclosed |
| US-20210251958-A1 | Antibacterial Compounds | RHODE ISLAND HOSPITAL, A LIFESPAN-PARTNER | 2021-08-19 | — | — | US | disclosed |
| WO-2019199979-A1 | ANTIBACTERIAL COMPOUNDS | THE GENERAL HOSPITAL CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11690824-B2 | Antibacterial compounds | MRPL21, SPOUT1, BAX | KDM4E 4594/4885ALDH1A1 2131/4885HPGD 502/4885 |
| US-20210251958-A1 | Antibacterial Compounds | MRPL21, SPOUT1, BAX | KDM4E 4594/4885ALDH1A1 2131/4885HPGD 502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.