Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10479725 | 0.89 | NAAA (0.44) | NAAAGAAMAPTHTTPOLB | |
| SCHEMBL10479724 | 0.89 | NAAA (0.44) | NAAAGAAMAPTHTTPOLB | |
| SCHEMBL10073834 | 0.89 | GAA (0.43) | NAAAGAAMAPTPPM1BPTPN1 | |
| SCHEMBL10480059 | 0.88 | NAAA (0.47) | NAAAGAAMAPTHTTEPHX2 | |
| SCHEMBL14926581 | 0.88 | ALDH1A1 (0.47) | NAAAGAAMAPTPPM1BPTPN1 | |
| SCHEMBL20032684 | 0.88 | ACHE (0.40) | NAAAGAAMAPTPPM1BPTPN1 | |
| SCHEMBL14926573 | 0.88 | MAPT (0.39) | NAAAGAAMAPTPPM1BPTPN1 | |
| SCHEMBL10480056 | 0.88 | NAAA (0.47) | NAAAGAAMAPTHTTEPHX2 | |
| SCHEMBL10479683 | 0.87 | GAA (0.43) | NAAAGAAMAPTPPM1BPTPN1 | |
| SCHEMBL10479678 | 0.87 | GAA (0.43) | NAAAGAAMAPTPPM1BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3677659-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2020-07-08 | — | — | EP | disclosed |
| EP-3130651-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-10-16 | — | — | EP | disclosed |