SCHEMBL21476832

SCHEMBL21476832

c1ccc2oc(-c3ccc(-c4cc(-c5ccc(-c6cccc7ccccc67)cc5)nc(-c5cccc6c5oc5ccccc56)n4)cc3)cc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.44
MAOB P27338 3/20 0.44
PTPRC P08575 1/20 0.41
PTPN1 P18031 1/20 0.41
ENPP3 O14638 1/20 0.41
ENPP1 P22413 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
MAOA P21397 2/20 0.39
PLA2G2A P14555 2/20 0.38
PLA2G4A P47712 2/20 0.38
METAP2 P50579 1/20 0.38
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 2/20 0.38
ALDH1A1 P00352 2/20 0.38
RAB9A P51151 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP19A1 P11511 1/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21476387 0.95 ALOX5 (0.44) ALOX5MAOBPTPRCPTPN1ENPP3
SCHEMBL21476499 0.93 ALOX5 (0.44) ALOX5MAOBPTPRCPTPN1CA1
SCHEMBL21476642 0.92 ALOX5 (0.45) ALOX5MAOBPTPRCPTPN1ENPP3
SCHEMBL21476569 0.91 ALOX5 (0.43) ALOX5MAOBPTPRCPTPN1CA1
SCHEMBL21480639 0.90 PLA2G2A (0.45) ALOX5MAOBPTPRCPTPN1CA1
SCHEMBL21476837 0.88 MAOB (0.44) ALOX5MAOBPTPRCPTPN1ENPP3
SCHEMBL21476384 0.88 ALOX5 (0.44) ALOX5MAOBPTPRCPTPN1MAOA
SCHEMBL21476820 0.88 MAOB (0.46) ALOX5MAOBPTPRCPTPN1ENPP3
SCHEMBL21476685 0.88 PLA2G2A (0.41) ALOX5MAOBPTPRCPTPN1CA1
SCHEMBL19397387 0.88 ALOX5 (0.48) ALOX5ENPP3ENPP1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210130336-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2021-05-06 US disclosed
WO-2019198806-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2019-10-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210130336-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE L1CAM, MLX, LEF1 ALOX5 3167/4885MAOB 2115/4885PTPRC 4495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.