Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31305176 | 1.00 | RECQL (0.43) | RECQLALDH1A1NCEH1TYMSKMT2A | |
| SCHEMBL5864493 | 0.78 | ADORA3 (0.46) | RECQLALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2432747 | 0.75 | PIM1 (0.53) | ALDH1A1KMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL2176042 | 0.74 | KDM4E (0.50) | RECQLALDH1A1TYMSKMT2AMAPT | |
| SCHEMBL19585641 | 0.74 | ALDH1A1 (0.59) | RECQLALDH1A1MAPTNPC1SMN1; SMN2 | |
| SCHEMBL15440586 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL21402707 | 0.73 | CYP19A1 (0.44) | KMT2AMAPTMEN1NPC1SMN1; SMN2 | |
| SCHEMBL31305190 | 0.72 | RECQL (0.43) | RECQLALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL11654706 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTMEN1NPC1 | |
| SCHEMBL823831 | 0.71 | SMN1; SMN2 (0.43) | RECQLALDH1A1NCEH1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190315775-A1 | MODIFIED PHENYLPHTHALIMIDE AND PHARMACEUTICAL COMPOSITION HAVING SAME AS ACTIVE INGREDIENT | KEIO UNIVERSITY (JP) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315775-A1 | MODIFIED PHENYLPHTHALIMIDE AND PHARMACEUTICAL COMPOSITION HAVING SAME AS ACTIVE INGREDIENT | HNRNPL, HNRNPLL, CCNL2 | RECQL 1574/4885ALDH1A1 2073/4885NCEH1 3823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.