Sugi Predict

Sugi Predict / Compounds / SCHEMBL2432747

SCHEMBL2432747

SCHEMBL2432747

CC(=O)Oc1ccc(OC(C)=O)c2c1C(=O)OC2=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PIM1 P11309 1/20 0.53
▸ KDM4E B2RXH2 5/20 0.46
▸ ALDH1A1 P00352 3/20 0.46
▸ TSHR P16473 3/20 0.46
▸ HPGD P15428 2/20 0.46
▸ PTGS2 P35354 2/20 0.46
▸ HSD17B10 Q99714 2/20 0.46
▸ ESR1 P03372 1/20 0.46
▸ ITGB3 P05106 1/20 0.46
▸ ITGA2B P08514 1/20 0.46
▸ HMGB1 P09429 1/20 0.46
▸ GGT1 P19440 1/20 0.46
▸ PTGS1 P23219 1/20 0.46
▸ BLM P54132 1/20 0.46
▸ NAPRT Q6XQN6 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ GAA P10253 1/20 0.44
▸ RAB9A P51151 1/20 0.44
▸ CA12 O43570 1/20 0.43
▸ CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2176042 0.83 KDM4E (0.50) PIM1KDM4EALDH1A1TSHRHPGD
SCHEMBL5864493 0.81 ADORA3 (0.46) PIM1KDM4EALDH1A1TSHRHPGD
SCHEMBL10378556 0.77 PIM1 (0.82) PIM1KDM4EALDH1A1TSHRHPGD
SCHEMBL497339 0.76 MAPT (0.60) PIM1KDM4EALDH1A1TSHRHPGD
SCHEMBL29551111 0.76 MAPT (0.60) PIM1KDM4EALDH1A1TSHRHPGD
SCHEMBL31305176 0.75 RECQL (0.43) PIM1KDM4EALDH1A1TSHRHPGD
SCHEMBL21477545 0.75 RECQL (0.43) PIM1KDM4EALDH1A1TSHRHPGD
SCHEMBL5817030 0.75 PIM1 (0.49) PIM1KDM4EALDH1A1TSHRHPGD
SCHEMBL30444670 0.73 KDM4E (0.59) PIM1KDM4EALDH1A1TSHRHPGD
SCHEMBL1287133 0.73 KDM4E (0.59) PIM1KDM4EALDH1A1TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107474007-B A kind of method preparing 3,6- dihydroxy benzenes dicarboximide 上海再启生物技术有限公司 2019-04-19 — — CN claimed
CN-107474007-A The method that one kind prepares 3,6 dihydroxy benzenes dicarboximides 上海再启生物技术有限公司 2017-12-15 — — CN claimed
CN-116646586-A Lithium ion battery and preparation method thereof 浙江锂威能源科技有限公司 2023-08-25 — — CN disclosed
CN-113231760-B Anisotropic conductive adhesive and adhesive film and preparation method thereof 深圳市福英达工业技术有限公司 2022-07-08 — — CN disclosed
CN-107474007-B A kind of method preparing 3,6- dihydroxy benzenes dicarboximide 上海再启生物技术有限公司 2019-04-19 — — CN disclosed
CN-107474007-A The method that one kind prepares 3,6 dihydroxy benzenes dicarboximides 上海再启生物技术有限公司 2017-12-15 — — CN disclosed
EP-2215082-B1 PHTHALAZINE AND PYRIDO[3,4-D]PYRIDAZINE COMPOUNDS AS H1 RECEPTOR ANTAGONISTS GLAXO GROUP LTD (GB) 2011-09-21 — — EP disclosed
EP-2007735-B1 2-SUBSTITUTED 4-BENZYLPHTHALAZINONE DERIVATIVES AS HISTAMINE H1 AND H3 ANTAGONISTS GLAXO GROUP LTD (GB) 2010-10-27 — — EP disclosed
US-20100216799-A1 PHTHALAZINE AND PYRIDO[3,4-D]PYRIDAZINE COMPOUNDS AS H1 RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2010-08-26 — — US disclosed
EP-2215082-A1 PHTHALAZINE AND PYRIDO Ý3,4-D¨PYRIDAZ INE COMPOUNDS AS H1 RECEPTOR ANTAGONISTS Glaxo Group Limited (GB) 2010-08-11 — — EP disclosed
US-20100184770-A1 COMPOUNDS GLAXO GROUP LIMITED 2010-07-22 — — US disclosed
US-20090105225-A1 2-Substituted 4-Benzylphthalazinone Derivatives as Histamine H1 and H3 Antagonists GLAXO GROUP LIMITED (GB) 2009-04-23 — — US disclosed
WO-2009047336-A1 PHTHALAZINE AND PYRIDO [3,4-D] PYRIDAZ INE COMPOUNDS AS H1 RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2009-04-16 — — WO disclosed
EP-2007735-A1 2-SUBSTITUTED 4-BENZYLPHTHALAZINONE DERIVATIVES AS HISTAMINE H1 AND H3 ANTAGONISTS Glaxo Group Limited (GB) 2008-12-31 — — EP disclosed
WO-2008074803-A2 4-BENZYL-L ( 2H) -PHTHALAZINONES AS H1 RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2008-06-26 — — WO disclosed
US-20080039444-A1 COMPOUNDS GLAXO GROUP LIMITED (GB) 2008-02-14 — — US disclosed
WO-2007122156-A9 2-SUBSTITUTED 4-BENZYLPHTHALAZINONE DERIVATIVES AS HISTAMINE H1 AND H3 ANTAGONISTS GLAXO GROUP LTD (GB) 2008-01-24 — — WO disclosed
WO-2007122156-A1 2-SUBSTITUTED 4-BENZYLPHTHALAZINONE DERIVATIVES AS HISTAMINE H1 AND H3 ANTAGONISTS GLAXO GROUP LIMITED (GB) 2007-11-01 — — WO disclosed
US-7009027-B2 Graft polymers formed by using polyesterimides having cyclic dicarboxylic anhydride end groups; blends used to form carpet filaments or fibers THUERINGISCHES INSTITUT FUER TEXTIL-UND KUNSTSTOFF-FORSCHUNG E.V. (DE) 2006-03-07 — — US disclosed
EP-1339773-B1 METHOD FOR PRODUCING MELTABLE POLYESTERS THUERINGISCHES INST TEXTIL (DE) 2005-02-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100216799-A1 PHTHALAZINE AND PYRIDO[3,4-D]PYRIDAZINE COMPOUNDS AS H1 RECEPTOR ANTAGONISTS HRH4, HRH2, HRH1 PIM1 4720/4885KDM4E 955/4885ALDH1A1 1732/4885
US-20100184770-A1 COMPOUNDS CMA1, TSLP, IL5 PIM1 4384/4885KDM4E 3155/4885ALDH1A1 516/4885
US-20080039444-A1 COMPOUNDS CMA1, MRGPRX2, HRH2 PIM1 4577/4885KDM4E 3049/4885ALDH1A1 292/4885
US-20090105225-A1 2-Substituted 4-Benzylphthalazinone Derivatives as Histamine H1 and H3 Antagonists HRH2, HRH3, HRH4 PIM1 3485/4885KDM4E 471/4885ALDH1A1 1188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.