Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720552 | 0.91 | EPHX1 (0.39) | ALDH1A1TSHRADH1BADH1CADH1A | |
| SCHEMBL719934 | 0.91 | EPHX1 (0.39) | ALDH1A1TSHRADH1BADH1CADH1A | |
| SCHEMBL540785 | 0.81 | HTT (0.39) | ALDH1A1KMT2AHTTTSHRGAA | |
| SCHEMBL13822511 | 0.75 | — | — | |
| SCHEMBL7227062 | 0.74 | HTT (0.41) | ALDH1A1KMT2AHTTTSHRMAPT | |
| SCHEMBL10409485 | 0.70 | ALDH1A1 (0.54) | ALDH1A1TSHRGAA | |
| SCHEMBL5367349 | 0.67 | LMNA (0.48) | ALDH1A1TSHRCNR1MAPTADH1B | |
| SCHEMBL13822665 | 0.67 | — | — | |
| SCHEMBL6767087 | 0.67 | TSHR (0.41) | ALDH1A1TSHRCNR1MAPTADH1B | |
| SCHEMBL236462 | 0.66 | TSHR (0.53) | ALDH1A1KMT2ATSHRMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019200161-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | DESIGN THERAPEUTICS INC. (US) | 2019-10-17 | — | — | WO | disclosed |