Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10431348 | 0.85 | KEAP1 (0.50) | ALDH1A1HPGDDUSP3PAOXGAA | |
| SCHEMBL540785 | 0.83 | HTT (0.39) | ALDH1A1HPGDGAASMN1; SMN2LMNA | |
| SCHEMBL22651218 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDDUSP3PAOXGAA | |
| SCHEMBL20796273 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HPGDDUSP3PAOXGAA | |
| SCHEMBL4312012 | 0.79 | HPGD (0.53) | ALDH1A1HPGDDUSP3PAOXGAA | |
| SCHEMBL8670292 | 0.78 | TSHR (0.40) | ALDH1A1PAOXSMN1; SMN2LMNAKCNH2 | |
| SCHEMBL23919511 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HPGDDUSP3PAOXGAA | |
| SCHEMBL7185320 | 0.76 | HTT (0.38) | ALDH1A1HPGDSMN1; SMN2LMNATSHR | |
| SCHEMBL22965525 | 0.76 | HPGD (0.50) | ALDH1A1HPGDDUSP3PAOXGAA | |
| SCHEMBL20099460 | 0.76 | HPGD (0.50) | ALDH1A1HPGDDUSP3PAOXGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4895840-A | ANTIARRHYTHMIA AGENTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-01-23 | — | — | US | disclosed |