Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720552 | 0.85 | EPHX1 (0.39) | ALDH1A1TSHRGNAI3GNAO1GNAI1 | |
| SCHEMBL719934 | 0.85 | EPHX1 (0.39) | ALDH1A1TSHRGNAI3GNAO1GNAI1 | |
| SCHEMBL8670292 | 0.83 | TSHR (0.40) | HTTALDH1A1SMN1; SMN2KCNH2KCNA5 | |
| SCHEMBL10409485 | 0.83 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KCNH2LMNAHPGD | |
| SCHEMBL7227062 | 0.83 | HTT (0.41) | HTTALDH1A1SMN1; SMN2KCNH2KCNA5 | |
| SCHEMBL21478037 | 0.81 | ALDH1A1 (0.33) | HTTALDH1A1MAPTKMT2APOLB | |
| SCHEMBL7185320 | 0.79 | HTT (0.38) | HTTALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL5911087 | 0.74 | KMT2A (0.39) | HTTALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8435127 | 0.71 | ALDH1A1 (0.54) | HTTALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL1514267 | 0.71 | ALDH1A1 (0.54) | HTTALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 586 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3035907-B1 | COSMETIC COMPOSITION COMPRISING AMINO SILICONES, CATIONIC SURFACTANTS AND SPECIFIC ESTERS AND A PROCESS FOR A COSMETIC TREATMENT | OREAL (FR) | 2019-04-03 | — | — | EP | claimed |
| EP-1707183-B2 | Dye composition comprising a non-ionic associative polymer, process for dyeing keratin fibres using same | OREAL (FR) | 2018-04-25 | — | — | EP | claimed |
| EP-2677995-B1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A DIRECT DYE BEARING A DISULFIDE/THIOL FUNCTION, A NONIONIC SURFACTANT, AN AMPHOTERIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'ORÉAL (FR) | 2017-04-26 | — | — | EP | claimed |
| EP-2074983-B1 | Method for preparing a cationic nanoemulsion and cosmetic composition | L'ORÉAL (FR) | 2017-03-15 | — | — | EP | claimed |
| EP-1674075-B1 | Hair colouring process comprising a cleaning step | ORÉAL L (FR) | 2016-07-20 | — | — | EP | claimed |
| EP-1707182-B2 | Dye composition comprising a fatty acid ester and process for dyeing keratin fibres using the same | ORÉAL L (FR) | 2014-09-10 | — | — | EP | claimed |
| EP-1707182-B1 | Dye composition comprising a fatty acid ester and process for dyeing keratin fibres using the same | OREAL (FR) | 2010-10-20 | — | — | EP | claimed |
| EP-1707190-B1 | Dye composition comprising a hydrophobically modified nonionic cellulose and method for dyeing keratin fibres using it | OREAL (FR) | 2010-10-20 | — | — | EP | claimed |
| EP-2196181-A2 | Cosmetic composition comprising at least one ortho-diphenol, one metal salt, hydrogen peroxide, (bi)carbonate and a surface-active agent, and dyeing method based on the composition | L'Oreal (FR) | 2010-06-16 | — | — | EP | claimed |
| EP-1707183-B1 | Dye composition comprising a non-ionic associative polymer, process for dyeing keratin fibres using same | OREAL (FR) | 2010-03-03 | — | — | EP | claimed |
| EP-1674075-A1 | Colored hair treating process with a composition comprising a specific non ionic surfactant and use to protect the coloration | L'OREAL (FR) | 2006-06-28 | — | — | EP | claimed |
| WO-2006013270-A2 | COSMETIC COMPOSITIONS CONTAINING AT LEAST ONE SURFACTANT AND AT LEAST ONE ETHYLENE COPOLYMER WITH POLYETHYLENE GLYCOL GRAFTS | L'ORÉAL (FR) | 2006-02-09 | — | — | WO | claimed |
| WO-2005092275-A1 | COSMETIC COMPOSITION COMPRISING A DENDRITIC POLYMER WITH PERIPHERAL FATTY CHAINS, A SURFACTANT AND A COSMETIC AGENT, AND USES THEREOF | L'OREAL (FR) | 2005-10-06 | — | — | WO | claimed |
| EP-1438951-A1 | Ready-to-use bleaching compositions, preparation process thereof and bleaching process therewith | L'OREAL (FR) | 2004-07-21 | — | — | EP | claimed |
| EP-1430867-A1 | Process to prepare a cationic nanoemulsion, and cosmetic composition. | L'OREAL (FR) | 2004-06-23 | — | — | EP | claimed |
| US-6692539-B2 | Cationic or amphoteric polymer whose cationic charge density is greater than or equal to 2 meq/gram. | L'OREAL (FR) | 2004-02-17 | — | — | US | claimed |
| US-20030172473-A1 | Composition useful for the oxidation dyeing of keratin fibres, containing an oxyalkylenated carboxylic acid ether, a nonionic surfactant and a particular polymer | L'OREAL (FR) | 2003-09-18 | — | — | US | claimed |
| EP-1329216-A1 | Composition for oxidative dyeing of keratinous fibers containing an oxyalkylene ether carboxylic acid, a non-ionic surfactant and a particulate polymer | L'OREAL (FR) | 2003-07-23 | — | — | EP | claimed |
| EP-1152735-A1 | COSMETIC COMPOSITIONS CONTAINING A QUATERNARY SILICON AND A PEARLING AGENT AND THEIR USES | L'OREAL (FR) | 2001-11-14 | — | — | EP | claimed |
| WO-2001041719-A1 | COSMETIC COMPOSITIONS CONTAINING A QUATERNARY SILICON AND A PEARLING AGENT AND THEIR USES | L'OREAL (FR) | 2001-06-14 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030172473-A1 | Composition useful for the oxidation dyeing of keratin fibres, containing an oxyalkylenated carboxylic acid ether, a nonionic surfactant and a particular polymer | KRT18, KRTCAP2, CUTA | HTT 2305/4885ALDH1A1 1206/4885SMN1; SMN2 4658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.