SCHEMBL2148128

SCHEMBL2148128

C=COC(=O)c1ncccc1C=C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.37
KDM4E B2RXH2 4/20 0.37
MAPT P10636 2/20 0.37
ALOX15 P16050 2/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
BLM P54132 1/20 0.37
AGER Q15109 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CYP1A2 P05177 1/20 0.33
BRD4 O60885 1/20 0.33
TRIM24 O15164 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33
NFE2L2 Q16236 1/20 0.33
HTT P42858 1/20 0.33
MYC P01106 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
EGLN2 Q96KS0 1/20 0.30
FTO Q9C0B1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16239167 0.83 L3MBTL1 (0.37) L3MBTL1KDM4EMAPTALOX15ALDH1A1
SCHEMBL535731 0.83 L3MBTL1 (0.55) L3MBTL1KDM4EMAPTALOX15ALDH1A1
SCHEMBL491212 0.81 KDM4E (0.46) L3MBTL1KDM4EMAPTALOX15ALDH1A1
SCHEMBL3466498 0.80 METAP1 (0.38) L3MBTL1KDM4EMAPTALOX15ALDH1A1
SCHEMBL754122 0.79 KDM4E (0.55) L3MBTL1KDM4EMAPTALOX15ALDH1A1
SCHEMBL31628026 0.77 ALDH1A1 (0.41) L3MBTL1KDM4EMAPTALOX15ALDH1A1
SCHEMBL16239166 0.77 KDM4E (0.40) L3MBTL1KDM4EMAPTALOX15ALDH1A1
SCHEMBL2840909 0.77 KDM4E (0.40) L3MBTL1KDM4EMAPTALOX15ALDH1A1
Hydrochloric Acid SCHEMBL16239168 0.77 KDM4E (0.53) L3MBTL1KDM4EMAPTALOX15ALDH1A1
SCHEMBL27668895 0.75 KDM4E (0.61) L3MBTL1KDM4EMAPTALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8541153-B2 Toner for developing electrostatic image, developer for electrostatic image, toner cartridge, process cartridge, image forming method, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2013-09-24 US disclosed
US-20110171572-A1 TONER FOR DEVELOPING ELECTROSTATIC IMAGE, DEVELOPER FOR ELECTROSTATIC IMAGE, TONER CARTRIDGE, PROCESS CARTRIDGE, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2011-07-14 US disclosed
US-20060115757-A1 Toner for development of electrostatic latent image, electrostatic latent image developer, and method for formation of image FUJI XEROX CO., LTD. (JP) 2006-06-01 US disclosed
US-6582867-B2 A crystalline binder resin and a fatty acid ester or a resin having a contact angle with water that is smaller than that of the crystalline resin; electrography; reproducibility in particle size/distribution; low-temperature fixing; stability FUJI XEROX CO., LTD. (JP) 2003-06-24 US disclosed
US-20020055050-A1 Toner for developing electrostatic latent image, process for producing the same, and process for forming image FUJI XEROX CO., LTD. (JP) 2002-05-09 US disclosed