Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL214829 | 0.72 | ALOX15 (0.60) | TDP1FDPSBLMSRCMAPT | |
| Naphthalene SCHEMBL19062553 | 0.64 | FDPS (0.56) | TDP1FDPSBLMSRC | |
| Pyrophosphoric Acid SCHEMBL4104677 | 0.64 | BLM (0.56) | TDP1FDPSBLMSRCNPC1 | |
| Naphthalene SCHEMBL10853041 | 0.64 | FDPS (0.56) | TDP1FDPSBLMSRC | |
| Biphenyl SCHEMBL8424826 | 0.62 | ACP3 (0.56) | TDP1FDPSBLMSRCNPC1 | |
| Pyrophosphoric Acid SCHEMBL31318897 | 0.62 | CA2 (0.53) | TDP1FDPSBLMSRCNPC1 | |
| Diphenylamine SCHEMBL28255752 | 0.61 | HSD17B10 (0.55) | TDP1FDPSBLMSRCNPC1 | |
| Biphenyl SCHEMBL17801640 | 0.60 | ACP3 (0.54) | TDP1FDPSBLMSRCNPC1 | |
| Pyrophosphoric Acid SCHEMBL3974840 | 0.60 | TDP1 (0.55) | ESR1TDP1FDPSBLMSRC | |
| Pyrophosphoric Acid SCHEMBL31169618 | 0.60 | TSHR (0.50) | TDP1FDPSBLMSRCNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401277-A1 | SALT OF TETRAHYDROTRIAZOLOPYRIDINE DERIVATIVE AND CRYSTAL THEREOF | Eisai R&D Management Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |