SCHEMBL21483087

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12490905	1.00	ALDH1A1 (0.48)	ALDH1A1MEN1KMT2ALMNAMAPT
	SCHEMBL21462564	1.00	ALDH1A1 (0.48)	ALDH1A1MEN1KMT2ALMNAMAPT
	SCHEMBL23464439	0.89	SIGMAR1 (0.49)	ALDH1A1MEN1KMT2ALMNAMAPT
	SCHEMBL20521716	0.85	GBA1 (0.47)	ALDH1A1MEN1KMT2ATSHRSIGMAR1
	SCHEMBL15398360	0.83	OPRD1 (0.48)	ALDH1A1MAPK1TSHRCYP3A4CYP2D6
	SCHEMBL21209747	0.82	OPRL1 (0.51)	ALDH1A1MEN1KMT2ALMNAMAPT
	SCHEMBL6331329	0.81	ALDH1A1 (0.49)	ALDH1A1MEN1KMT2ALMNAMAPT
	SCHEMBL29797081	0.81	ALDH1A1 (0.56)	ALDH1A1MEN1KMT2ALMNAMAPT
	SCHEMBL5871849	0.79	SIGMAR1 (0.46)	ALDH1A1MEN1KMT2ALMNAMAPT
	SCHEMBL22528005	0.79	ACHE (0.50)	ALDH1A1MEN1KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.