Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GRK2 | P25098 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28063097 | 0.86 | MAPK1 (0.67) | RAB9ALMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL1562128 | 0.85 | ALDH1A1 (0.57) | RAB9ALMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL24811439 | 0.84 | RAB9A (0.62) | RAB9ALMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL19897705 | 0.83 | HDAC3 (0.52) | RAB9ALMNAKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL8556893 | 0.80 | KMT2A (0.77) | RAB9AKMT2AMEN1POLBNPC1 | |
| SCHEMBL5429131 | 0.80 | RAB9A (0.56) | RAB9ALMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL5360905 | 0.79 | L3MBTL1 (0.58) | RAB9ALMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL15480414 | 0.79 | HDAC1 (0.69) | RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL2675404 | 0.79 | ALDH1A1 (0.68) | RAB9AL3MBTL1ALDH1A1POLBTDP1 | |
| SCHEMBL1238330 | 0.79 | HDAC3 (0.66) | RAB9ALMNAL3MBTL1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019197549-A1 | PYRAZOLO-TRIAZINE AND/OR PYRAZOLO-PYRIMIDINE DERIVATIVES AS SELECTIVE INHIBITOR OF CYCLIN DEPENDENT KINASE | QURIENT CO., LTD. (KR) | 2019-10-17 | — | — | WO | disclosed |