SCHEMBL21484913

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21505934	0.89	ADORA3 (0.50)	ADORA3LMNAMAPTHTTTDP1
	SCHEMBL21505933	0.89	SLC2A1 (0.53)	ADORA3LMNAMAPTHTTTDP1
	SCHEMBL21484775	0.87	MRE11 (0.51)	ADORA3LMNAMAPTKMT2AALDH1A1
	SCHEMBL21484670	0.86	MRE11 (0.61)	ADORA3LMNAMAPTHTTTDP1
	SCHEMBL21484598	0.86	MRE11 (0.57)	ADORA3LMNAMAPTTDP1GAA
	SCHEMBL21505948	0.85	FTO (0.43)	LMNAMAPTHTTGAAKMT2A
	SCHEMBL21484620	0.84	MRE11 (0.60)	LMNAMAPTGAAKMT2AALDH1A1
	SCHEMBL21484918	0.82	GSTO1 (0.49)	LMNAMAPTHTTKMT2AALDH1A1
	SCHEMBL21484921	0.82	MRE11 (0.47)	LMNAMAPTHTTGAAKMT2A
	SCHEMBL21484719	0.81	MRE11 (0.59)	LMNAMAPTKMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.