Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306384 | 0.74 | GABRA1 (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8129656 | 0.74 | ACACB (0.39) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL1306505 | 0.72 | APP (0.41) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL13397172 | 0.72 | NR1H2 (0.31) | — | |
| SCHEMBL17464776 | 0.72 | ACACB (0.41) | — | |
| SCHEMBL701214 | 0.72 | CYP2A6 (0.43) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL1535167 | 0.72 | GSK3B (0.46) | — | |
| SCHEMBL17464783 | 0.72 | ACACB (0.41) | — | |
| SCHEMBL3148515 | 0.71 | ACACB (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL23977506 | 0.71 | NOS3 (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019201865-A1 | SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES | MASARYKOVA UNIVERZITA (CZ) | 2019-10-24 | — | — | WO | disclosed |