Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | ADK | P55263 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17464783 | 0.98 | ACACB (0.41) | ACACBADKGRM5NOTUMTYR | |
| SCHEMBL17464776 | 0.98 | ACACB (0.41) | ACACBADKGRM5NOTUMTYR | |
| SCHEMBL30200615 | 0.83 | ADRB2 (0.43) | ADKFFAR1GABRA1GABRG2GABRB3 | |
| SCHEMBL21673923 | 0.83 | ADRB2 (0.43) | ADKFFAR1GABRA1GABRG2GABRB3 | |
| SCHEMBL28977400 | 0.83 | NOS3 (0.40) | ACACBFFAR1GABRA1GABRG2GABRB3 | |
| SCHEMBL23977506 | 0.83 | NOS3 (0.40) | ACACBFFAR1GABRA1GABRG2GABRB3 | |
| SCHEMBL1306384 | 0.83 | GABRA1 (0.38) | GRM5GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL8141103 | 0.81 | ACACB (0.50) | ACACBADKTYRFFAR1HTT | |
| SCHEMBL1306505 | 0.81 | APP (0.41) | GRM5GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL2609821 | 0.81 | ACACB (0.38) | ACACBADKGRM5NOTUMTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150218110-A1 | USE OF SUBSTITUTED BENZODIAZEPINONES AND BENZAZEPINONES OR THE SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-08-06 | — | — | US | disclosed |
| US-20150218110-A1 | USE OF SUBSTITUTED BENZODIAZEPINONES AND BENZAZEPINONES OR THE SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-08-06 | — | — | US | disclosed |
| US-20150216168-A1 | USE OF SUBSTITUTED 2-AMIDOBENZIMIDAZOLES, 2-AMIDOBENZOXAZOLES AND 2-AMIDOBENZOTHIAZOLES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-08-06 | — | — | US | disclosed |
| US-20150216168-A1 | USE OF SUBSTITUTED 2-AMIDOBENZIMIDAZOLES, 2-AMIDOBENZOXAZOLES AND 2-AMIDOBENZOTHIAZOLES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-08-06 | — | — | US | disclosed |
| US-7595407-B2 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-09-29 | — | — | US | disclosed |
| US-7595407-B2 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-09-29 | — | — | US | disclosed |
| US-7423160-B2 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-09-09 | — | — | US | disclosed |
| US-20080071093-A1 | BORON COMPLEXATION STRATEGY FOR USE IN MANIPULATING 1-ACYLDIPYRROMETHANES | LINDSEY JONATHAN S | 2008-03-20 | — | — | US | disclosed |
| US-20080071093-A1 | BORON COMPLEXATION STRATEGY FOR USE IN MANIPULATING 1-ACYLDIPYRROMETHANES | LINDSEY JONATHAN S | 2008-03-20 | — | — | US | disclosed |
| US-20080027232-A1 | BORON COMPLEXATION STRATEGY FOR USE IN MANIPULATING 1-ACYLDIPYRROMETHANES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-01-31 | — | — | US | disclosed |
| US-7317108-B2 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-01-08 | — | — | US | disclosed |
| US-7282582-B2 | Boron complexation strategy for use in manipulating 1-acyldipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-10-16 | — | — | US | disclosed |
| US-20070088158-A1 | BORON COMPLEXATION STRATEGY FOR USE IN MANIPULATING 1-ACYLDIPYRROMETHANES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-04-19 | — | — | US | disclosed |
| US-6030969-A | ADENOSINE KINASE INHIBITORS; ANTIISCHEMIA,-INFLAMMATORY, -DIABETIC AGENTS; NEUROLOGICAL AND GASTROINTESTINAL DISORDERS; NOCIPERCEPTION, IMMUNOSUPPRESSION; SEPSIS | ABBOTT LABORATORIES (US) | 2000-02-29 | — | — | US | disclosed |
| EP-0975633-A1 | 5,6,7-TRISUBSTITUTED-4-AMINOPYRIDOL 2,3-D]PYRIMIDINE COMPOUNDS | Abbott Laboratories (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046604-A1 | 5,6,7-TRISUBSTITUTED-4-AMINOPYRIDOL[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 1998-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088158-A1 | BORON COMPLEXATION STRATEGY FOR USE IN MANIPULATING 1-ACYLDIPYRROMETHANES | DECR2, ANTXR2, CD79B | ACACB 2332/4885ADK 4101/4885GRM5 948/4885 |
| US-20150218110-A1 | USE OF SUBSTITUTED BENZODIAZEPINONES AND BENZAZEPINONES OR THE SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | GABBR1, GABRA1, GABRA6 | ACACB 2332/4885ADK 271/4885GRM5 424/4885 |
| US-20080071093-A1 | BORON COMPLEXATION STRATEGY FOR USE IN MANIPULATING 1-ACYLDIPYRROMETHANES | DECR2, ANTXR2, CD79B | ACACB 2332/4885ADK 4101/4885GRM5 948/4885 |
| US-20080027232-A1 | BORON COMPLEXATION STRATEGY FOR USE IN MANIPULATING 1-ACYLDIPYRROMETHANES | DECR2, ANTXR2, CD79B | ACACB 2332/4885ADK 4101/4885GRM5 948/4885 |
| US-20150216168-A1 | USE OF SUBSTITUTED 2-AMIDOBENZIMIDAZOLES, 2-AMIDOBENZOXAZOLES AND 2-AMIDOBENZOTHIAZOLES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | ABAT, AAK1, AGXT | ACACB 406/4885ADK 260/4885GRM5 2867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.