Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | USP9X | Q93008 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4349469 | 0.79 | GAA (0.50) | GAAALDH1A1TSHRCA1CA2 | |
| SCHEMBL21145969 | 0.78 | MMP13 (0.43) | MMP13HTR2CHIF1AALDH1A1CA1 | |
| SCHEMBL16415970 | 0.76 | SLC6A2 (0.43) | GAAALDH1A1TSHRACHE | |
| SCHEMBL28024313 | 0.76 | HIF1A (0.42) | MMP13HTR2CHIF1ACA1CA2 | |
| SCHEMBL7361147 | 0.76 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16957130 | 0.76 | HTR2C (0.37) | MMP13HTR2CHIF1AUSP9XALDH1A1 | |
| SCHEMBL24758006 | 0.75 | HIF1A (0.41) | HTR2CHIF1APTGDR2CA1CA2 | |
| SCHEMBL21495012 | 0.75 | ALDH1A1 (0.53) | GAAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL15974455 | 0.75 | ALDH1A1 (0.53) | GAAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL20425124 | 0.75 | LMNA (0.44) | GAAALDH1A1TSHRHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019201865-A1 | SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES | MASARYKOVA UNIVERZITA (CZ) | 2019-10-24 | — | — | WO | disclosed |