Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28521283 | 0.89 | RAB9A (0.35) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL21484640 | 0.81 | MEN1 (0.43) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL21495060 | 0.75 | ALDH1A1 (0.41) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL21484702 | 0.74 | KMT2A (0.46) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL21505301 | 0.70 | USP30 (0.39) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL21495079 | 0.68 | MAPT (0.48) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL21495081 | 0.68 | SCN1A (0.61) | MEN1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL21495053 | 0.67 | NPC1 (0.36) | KMT2ARAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL21495067 | 0.67 | MAPT (0.51) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL23212669 | 0.66 | DRD3 (0.33) | MEN1KMT2ARAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019201865-A1 | SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES | MASARYKOVA UNIVERZITA (CZ) | 2019-10-24 | — | — | WO | disclosed |