Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21495060 | 0.77 | ALDH1A1 (0.41) | NPC1KMT2ARAB9AALDH1A1KDM4E | |
| SCHEMBL21495058 | 0.67 | MEN1 (0.38) | NPC1KMT2ARAB9AL3MBTL1HPGD | |
| SCHEMBL1691061 | 0.65 | MAPT (0.68) | NPC1KMT2ARAB9AL3MBTL1HPGD | |
| SCHEMBL15314157 | 0.65 | HTR3E (0.38) | RAB9ARECQL | |
| SCHEMBL20043318 | 0.65 | CYP3A4 (0.31) | — | |
| SCHEMBL15314170 | 0.62 | CYP3A4 (0.35) | RAB9AMAPT | |
| SCHEMBL21066336 | 0.62 | L3MBTL1 (0.54) | NPC1RAB9AL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL367981 | 0.61 | SMN1; SMN2 (0.51) | NPC1KMT2ARAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL20043393 | 0.61 | — | — | |
| SCHEMBL15314158 | 0.61 | CCR1 (0.39) | NPC1KMT2ARAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019201865-A1 | SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES | MASARYKOVA UNIVERZITA (CZ) | 2019-10-24 | — | — | WO | disclosed |