Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21484642 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| SCHEMBL21495053 | 0.77 | NPC1 (0.36) | ALDH1A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL21495058 | 0.75 | MEN1 (0.38) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| SCHEMBL21495080 | 0.69 | MAPT (0.46) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| SCHEMBL19031383 | 0.69 | ABL1 (0.44) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| SCHEMBL21495082 | 0.68 | RAB9A (0.63) | ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL21495070 | 0.68 | WNT3A (0.51) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| SCHEMBL21484611 | 0.65 | WNT3A (0.48) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| SCHEMBL23212669 | 0.65 | DRD3 (0.33) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| SCHEMBL31043570 | 0.63 | LMNA (0.55) | ALDH1A1RAB9ASMN1; SMN2NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019201865-A1 | SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES | MASARYKOVA UNIVERZITA (CZ) | 2019-10-24 | — | — | WO | disclosed |