SCHEMBL2149647

SCHEMBL2149647

Brc1cc(-c2cc3ccccc3o2)c(Br)cc1-c1cc2ccccc2o1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.76
MAOA P21397 5/20 0.76
CA2 P00918 2/20 0.47
CA1 P00915 1/20 0.47
CA9 Q16790 1/20 0.47
ALOX5 P09917 1/20 0.47
RAB9A P51151 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
PTPRC P08575 1/20 0.46
PTPN1 P18031 1/20 0.46
NPC1 O15118 2/20 0.46
MAPT P10636 1/20 0.46
TDP1 Q9NUW8 1/20 0.45
ADRA2A P08913 2/20 0.45
METAP2 P50579 1/20 0.45
F2RL3 Q96RI0 1/20 0.44
HTR2C P28335 1/20 0.44
GRM4 Q14833 1/20 0.44
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20174691 0.86 MAOB (1.00) MAOBMAOACA2CA1CA9
SCHEMBL11672377 0.85 MAOB (0.72) MAOBMAOACA2CA1CA9
SCHEMBL20175207 0.83 MAOB (0.68) MAOBMAOACA2CA1CA9
SCHEMBL20175208 0.83 MAOB (0.68) MAOBMAOACA2CA1CA9
SCHEMBL12854020 0.81 MAOB (0.71) MAOBMAOACA2CA1CA9
SCHEMBL61411 0.81 MAOB (0.71) MAOBMAOACA2CA1CA9
SCHEMBL12334463 0.81 MAOB (0.56) MAOBMAOACA2CA1CA9
SCHEMBL103158 0.80 MAOB (0.63) MAOBMAOACA2CA1CA9
SCHEMBL30036439 0.80 MAOB (0.63) MAOBMAOACA2CA1CA9
SCHEMBL19497662 0.79 MAOB (0.63) MAOBMAOACA2CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110166362-A1 NOVEL COMPOUND AND ORGANIC SEMICONDUCTOR MATERIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-07 US disclosed
EP-2341051-A1 NOVEL COMPOUND AND ORGANIC SEMICONDUCTOR MATERIAL Sumitomo Chemical Company, Limited (JP) 2011-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166362-A1 NOVEL COMPOUND AND ORGANIC SEMICONDUCTOR MATERIAL SCLY, MSRB3, SOD1 MAOB 180/4885MAOA 688/4885CA2 2630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.