Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497773 | 0.85 | HSD11B1 (0.43) | MEN1KMT2AHSD11B1LMNATSHR | |
| SCHEMBL23116738 | 0.83 | MEN1 (0.56) | MEN1KMT2ACYP19A1LMNACYP2A6 | |
| SCHEMBL29092067 | 0.79 | MEN1 (0.65) | MEN1KMT2AHSD11B1CYP19A1LMNA | |
| SCHEMBL29091903 | 0.79 | MEN1 (0.65) | MEN1KMT2AHSD11B1CYP19A1LMNA | |
| SCHEMBL25071163 | 0.79 | MEN1 (0.52) | MEN1KMT2ACYP19A1LMNACYP2A6 | |
| SCHEMBL29091899 | 0.79 | MEN1 (0.65) | MEN1KMT2AHSD11B1CYP19A1LMNA | |
| SCHEMBL809832 | 0.77 | LMNA (0.50) | MEN1KMT2ACYP19A1LMNACYP2A6 | |
| SCHEMBL16277011 | 0.77 | TSHR (0.55) | MEN1KMT2AHSD11B1LMNATSHR | |
| SCHEMBL1538386 | 0.77 | MEN1 (0.62) | MEN1KMT2ACYP19A1LMNACYP2A6 | |
| SCHEMBL13379568 | 0.77 | CYP19A1 (0.67) | MEN1KMT2ACYP19A1LMNACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450286-B2 | Compounds and compositions for inhibition of FASN | FORMA THERAPEUTICS, INC. (US) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450286-B2 | Compounds and compositions for inhibition of FASN | FASN, FABP1, SCD | MEN1 4044/4885KMT2A 4666/4885HSD11B1 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.