Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21497367 | 0.90 | HSD11B1 (0.39) | HSD11B1TSHRESR1ESR2LMNA | |
| SCHEMBL16277011 | 0.90 | TSHR (0.55) | HSD11B1TSHRLMNATYRHPGD | |
| SCHEMBL15280394 | 0.87 | TSHR (0.60) | HSD11B1TSHRALDH1A1KIF11 | |
| SCHEMBL14309198 | 0.85 | ESR1 (0.62) | TSHRESR1ESR2LMNATYR | |
| SCHEMBL1085590 | 0.85 | CA1 (0.46) | HSD11B1ALDH1A1KIF11MEN1KMT2A | |
| SCHEMBL21497366 | 0.85 | MEN1 (0.56) | HSD11B1TSHRLMNASLC6A2SLC6A4 | |
| SCHEMBL8657822 | 0.85 | KIF11 (0.54) | HSD11B1CYP3A4HPGDALDH1A1KIF11 | |
| SCHEMBL3621303 | 0.83 | ALDH1A1 (0.58) | HSD11B1TSHRESR1ESR2CYP3A4 | |
| SCHEMBL22931098 | 0.83 | TSHR (0.48) | HSD11B1TSHRESR1ESR2LMNA | |
| SCHEMBL24137113 | 0.81 | SLC2A1 (0.56) | TSHRLMNACYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106222-B2 | Fluorine-containing ether compound | FUJIFILM CORPORATION (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20090018350-A1 | NOVEL FLUORINE-CONTAINING ETHER COMPOUND | FUJIFILM CORPORATION (JP) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018350-A1 | NOVEL FLUORINE-CONTAINING ETHER COMPOUND | AFF4, AFF1, AFF2 | HSD11B1 1270/4885TSHR 530/4885ESR1 319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.