Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21498275 | 0.82 | ADORA2A (0.41) | CYP1A1CYP1A2ADORA2AALDH1A1LMNA | |
| SCHEMBL21498278 | 0.81 | CYP1A1 (0.55) | CYP1A1CYP1A2ADORA2AALDH1A1LMNA | |
| SCHEMBL24796288 | 0.79 | LMNA (0.46) | CYP1A1CYP1A2ADORA2AALDH1A1LMNA | |
| SCHEMBL19299387 | 0.78 | CYP2A6 (0.52) | CYP1A1CYP1A2ADORA2AALDH1A1LMNA | |
| SCHEMBL19299618 | 0.78 | RAB9A (0.48) | CYP1A2ADORA2ALMNAMAPTMEN1 | |
| SCHEMBL19299405 | 0.77 | MAOB (0.53) | ADORA2AALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL23989075 | 0.77 | MAPT (0.53) | ADORA2AALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30519266 | 0.76 | ADORA2A (0.55) | CYP1A2PTGS2PTGS1ADORA2AALDH1A1 | |
| SCHEMBL19283489 | 0.76 | ADORA2A (0.55) | CYP1A2PTGS2PTGS1ADORA2AALDH1A1 | |
| SCHEMBL21498269 | 0.76 | LMNA (0.50) | CYP1A2PTGS2PTGS1ADORA2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11538996-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| EP-3419960-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-07-01 | — | — | EP | disclosed |
| US-10454041-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10454041-B2 | Materials for organic electroluminescent devices | RIF1, INTS9, LEF1 | CYP1A1 20/4885CYP1A2 118/4885BRD4 2765/4885 |
| US-11538996-B2 | Materials for organic electroluminescent devices | RIF1, INTS9, LEF1 | CYP1A1 20/4885CYP1A2 118/4885BRD4 2765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.