SCHEMBL19299405

SCHEMBL19299405

O=C1c2ccccc2-c2cccc(-c3cccc(Cl)c3)c21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.53
S100A4 P26447 2/20 0.52
IDO1 P14902 3/20 0.49
HSP90AA1 P07900 2/20 0.48
HSP90AB1 P08238 2/20 0.48
PTPRC P08575 2/20 0.47
NAT1 P18440 1/20 0.47
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
GAA P10253 1/20 0.45
LMNA P02545 3/20 0.43
MAPT P10636 3/20 0.43
ALDH1A1 P00352 1/20 0.43
DNMT1 P26358 1/20 0.42
DNMT3L Q9UJW3 1/20 0.42
DNMT3A Q9Y6K1 1/20 0.42
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
DHODH Q02127 1/20 0.42
APAF1 O14727 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19299465 0.92 MEN1 (0.50) MAOBS100A4IDO1HSP90AA1HSP90AB1
SCHEMBL19299407 0.86 LMNA (0.47) MAOBS100A4IDO1HSP90AA1HSP90AB1
SCHEMBL21498269 0.85 LMNA (0.50) MAOBS100A4PTPRCMEN1KMT2A
SCHEMBL19299421 0.83 S100A4 (0.50) MAOBS100A4IDO1PTPRCLMNA
SCHEMBL19299390 0.83 S100A4 (0.62) MAOBS100A4IDO1HSP90AA1HSP90AB1
SCHEMBL30519266 0.81 ADORA2A (0.55) MAOBS100A4IDO1HSP90AA1HSP90AB1
SCHEMBL19283489 0.81 ADORA2A (0.55) MAOBS100A4IDO1HSP90AA1HSP90AB1
SCHEMBL19001705 0.81 MAPT (0.58) S100A4PTPRCMEN1KMT2ALMNA
SCHEMBL19299408 0.81 S100A4 (0.61) MAOBS100A4HSP90AA1HSP90AB1PTPRC
SCHEMBL19299394 0.81 PTPRC (0.44) MAOBS100A4IDO1HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230373941-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-11-23 US disclosed
US-20230373941-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-11-23 US disclosed
EP-4255151-A2 SPIRO[FLUORENE-9,9'-(THIO)XANTHENE] COMPOUNDS Merck Patent GmbH (DE) 2023-10-04 EP disclosed
EP-3645501-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-08-23 EP disclosed
EP-4113643-B1 SPIRO[FLUORENE-9,9'-(THIO)XANTHENE] COMPOUNDS MERCK PATENT GMBH (DE) 2023-08-09 EP disclosed
EP-3523834-B1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2023-01-25 EP disclosed
EP-4113643-A1 ELECTRONIC DEVICE Merck Patent GmbH (DE) 2023-01-04 EP disclosed
US-11538996-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-12-27 US disclosed
WO-2021214348-A2 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-10-28 WO disclosed
EP-3419960-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-07-01 EP disclosed
US-20200136045-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-04-30 US disclosed
US-20200044160-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2020-02-06 US disclosed
US-10454041-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2019-10-22 US disclosed
WO-2019002190-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-01-03 WO disclosed
WO-2017144150-A2 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10454041-B2 Materials for organic electroluminescent devices RIF1, INTS9, LEF1 MAOB 1038/4885S100A4 1308/4885IDO1 249/4885
US-20230373941-A1 COMPOUNDS FOR ELECTRONIC DEVICES CYP2E1, GPX1, ERCC1 MAOB 557/4885S100A4 997/4885IDO1 3452/4885
US-11538996-B2 Materials for organic electroluminescent devices RIF1, INTS9, LEF1 MAOB 1038/4885S100A4 1308/4885IDO1 249/4885
US-20200044160-A1 ELECTRONIC DEVICE XDH, AOX1, OCIAD1 MAOB 197/4885S100A4 1515/4885IDO1 2830/4885
US-20200136045-A1 MATERIALS FOR ELECTRONIC DEVICES SELE, SDHB, HCN2 MAOB 362/4885S100A4 682/4885IDO1 4358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.