Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21468501 | 0.85 | DHODH (0.39) | SMN1; SMN2ALDH1A1RAB9AHPGDMEN1 | |
| SCHEMBL21499348 | 0.79 | MAPT (0.59) | SMN1; SMN2ALDH1A1RAB9AHPGDMEN1 | |
| SCHEMBL21468460 | 0.77 | DHODH (0.59) | SMN1; SMN2ALDH1A1RAB9AHPGDMEN1 | |
| SCHEMBL21499351 | 0.72 | PDE7A (0.47) | SMN1; SMN2ALDH1A1RAB9AHPGDMEN1 | |
| SCHEMBL21468476 | 0.67 | RAB9A (0.52) | SMN1; SMN2ALDH1A1RAB9AHPGDMEN1 | |
| SCHEMBL21499381 | 0.64 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1RAB9AHPGDMEN1 | |
| SCHEMBL21468481 | 0.63 | DHODH (0.57) | SMN1; SMN2ALDH1A1RAB9AHPGDMEN1 | |
| SCHEMBL12868672 | 0.63 | HPGD (0.41) | SMN1; SMN2ALDH1A1RAB9AHPGDLMNA | |
| SCHEMBL21468486 | 0.63 | DHODH (0.65) | SMN1; SMN2ALDH1A1RAB9AHPGDMEN1 | |
| SCHEMBL21499392 | 0.62 | MAPT (0.53) | SMN1; SMN2ALDH1A1RAB9AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450263-B2 | Benzo annulenes as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450263-B2 | Benzo annulenes as antiviral agents | MAVS, ZC3HAV1, GABBR1 | SMN1; SMN2 804/4885ALDH1A1 187/4885RAB9A 1314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.