Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412021 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1MAPK1SMN1; SMN2POLBCYP3A4 | |
| SCHEMBL22289594 | 0.79 | CYP3A4 (0.40) | ALDH1A1MAPK1SMN1; SMN2CYP3A4CHRM1 | |
| SCHEMBL28251597 | 0.79 | LMNA (0.42) | ALDH1A1MAPK1SMN1; SMN2POLBCYP3A4 | |
| SCHEMBL31576176 | 0.77 | CYP3A4 (0.39) | ALDH1A1MAPK1SMN1; SMN2CYP3A4CHRM1 | |
| SCHEMBL21606931 | 0.75 | KMT2A (0.39) | ALDH1A1MAPK1SMN1; SMN2POLBCYP3A4 | |
| SCHEMBL21287461 | 0.75 | NOS2 (0.44) | ALDH1A1CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL9215459 | 0.75 | LMNA (0.35) | ALDH1A1MAPK1SMN1; SMN2POLBKDM4E | |
| SCHEMBL9215463 | 0.75 | NR4A2 (0.48) | ALDH1A1MAPK1SMN1; SMN2POLBCYP3A4 | |
| SCHEMBL10774397 | 0.75 | KDM4E (0.50) | ALDH1A1MAPK1SMN1; SMN2POLBCYP3A4 | |
| SCHEMBL29721960 | 0.75 | NOS2 (0.44) | ALDH1A1CYP3A4CHRM1ALOX15MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10889593-B2 | Compounds targeting proteins, compositions, methods, and uses thereof | BIOTHERYX, INC. (US) | 2021-01-12 | — | — | US | disclosed |
| US-20190322683-A1 | COMPOUNDS TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF | BIOTHERYX, INC. | 2019-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10889593-B2 | Compounds targeting proteins, compositions, methods, and uses thereof | CKS1B, IKZF3, EPAS1 | ALDH1A1 2758/4885MAPK1 838/4885SMN1; SMN2 2944/4885 |
| US-20190322683-A1 | COMPOUNDS TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF | CKS1B, IKZF3, EPAS1 | ALDH1A1 2758/4885MAPK1 838/4885SMN1; SMN2 2944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.