Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | MARS2 | Q96GW9 | 2/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28301168 | 0.74 | LTA4H (0.56) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL3840431 | 0.74 | LTA4H (0.50) | SLC6A4HTR2AKCNH2MEN1KMT2A | |
| SCHEMBL11377807 | 0.74 | LTA4H (0.55) | ALDH1A1 | |
| SCHEMBL23528205 | 0.73 | CHRM2 (0.50) | — | |
| SCHEMBL4510419 | 0.71 | ALDH1A1 (0.53) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL8340513 | 0.71 | SLC6A4 (0.47) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL5436691 | 0.71 | SLC6A4 (0.48) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL13887881 | 0.70 | SLC6A4 (0.68) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL11476835 | 0.70 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL12806377 | 0.70 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996926-A | Indole compounds as androgen receptor modulators | 尼多生物科学有限公司 | 2023-04-21 | — | — | CN | disclosed |
| US-11014926-B2 | Pyrrolo-, pyrazolo-, imidazo-pyrimidine and pyridine compounds that inhibit MNK1 and MNK2 | EFFECTOR THERAPEUTICS, INC. (US) | 2021-05-25 | — | — | US | disclosed |
| US-20190330216-A1 | PYRROLO-, PYRAZOLO-, IMIDAZO-PYRIMIDINE AND PYRIDINE COMPOUNDS THAT INHIBIT MNK1 AND MNK2 | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330216-A1 | PYRROLO-, PYRAZOLO-, IMIDAZO-PYRIMIDINE AND PYRIDINE COMPOUNDS THAT INHIBIT MNK1 AND MNK2 | NEK9, NEK2, TYK2 | SLC6A4 3918/4885HTR2A 2769/4885KCNH2 1544/4885 |
| US-11014926-B2 | Pyrrolo-, pyrazolo-, imidazo-pyrimidine and pyridine compounds that inhibit MNK1 and MNK2 | NEK9, NEK2, TYK2 | SLC6A4 3918/4885HTR2A 2769/4885KCNH2 1544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.