SCHEMBL2152199

SCHEMBL2152199

O=[N+]([O-])c1ccc(NC23CC4CC(CC(C4)C2)C3)nc1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.49
KMT2A Q03164 6/20 0.49
MAPT P10636 5/20 0.49
GAA P10253 2/20 0.49
LMNA P02545 1/20 0.49
CYP1A2 P05177 1/20 0.49
ALOX12 P18054 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
POLB P06746 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.44
RAB9A P51151 5/20 0.44
NPC1 O15118 3/20 0.44
ALDH1A1 P00352 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11446820 0.78 ALDH1A1 (0.57) MEN1KMT2AMAPTGAALMNA
SCHEMBL2152203 0.78 GAA (0.51) MEN1KMT2AMAPTGAALMNA
SCHEMBL6234527 0.76 NPC1 (0.47) MEN1KMT2AMAPTGAALMNA
SCHEMBL20796131 0.73 MEN1 (0.74) MEN1KMT2AMAPTGAALMNA
SCHEMBL7976984 0.73 RAB9A (0.43) MAPTLMNASMN1; SMN2POLBL3MBTL1
SCHEMBL2792832 0.72 ALDH1A1 (0.51) MEN1KMT2AMAPTGAALMNA
SCHEMBL3943376 0.72 MEN1 (0.62) MEN1KMT2AMAPTGAALMNA
SCHEMBL2793284 0.72 GAA (0.58) MEN1KMT2AMAPTGAALMNA
SCHEMBL8503182 0.71 KMT2A (0.60) MEN1KMT2AMAPTGAALMNA
SCHEMBL930847 0.71 GAA (0.65) MEN1KMT2AMAPTGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1241516-B1 Sum frequency light generation method and sum frequency light generation apparatus adaptable for wide-band wavelength conversion ANRITSU CORP (JP) 2008-06-25 EP claimed
US-6941051-B2 Method for producing non-linear optical organic crystal film REVEO, INC. (US) 2005-09-06 US claimed
CN-1636164-A Composite nonlinear optical film, manufacturing method and application thereof REVEO INC (US) 2005-07-06 CN claimed
US-6697395-B2 Sum frequency light generation method and sum frequency light generation apparatus adapatble for wide-band wavelength conversion ANRITSU CORPORATION (JP) 2004-02-24 US claimed
US-20040033038-A1 Method for producing non-linear optical organic crystal film XU JIANJUN (US) 2004-02-19 US claimed
US-6608205-B1 Single crystal thin films; electro-optics; strength, durabi-lity UNIVERSITY OF PUERTO RICO 2003-08-19 US claimed
US-6577798-B2 Method for producing non-linear optical organic crystal film REVEO, INC. 2003-06-10 US claimed
US-20020141459-A1 Sum frequency light generation method and sum frequency light generation apparatus adaptable for wide-band wavelength conversion ANRITSU CORPORATION (JP) 2002-10-03 US claimed
EP-1241516-A2 Sum frequency light generation method and sum frequency light generation apparatus adaptable for wide-band wavelength conversion ANRITSU CORPORATION (JP) 2002-09-18 EP claimed
US-20020041427-A1 Method for producing non-linear optical organic crystal film REVEO, INC. 2002-04-11 US claimed
WO-2002008828-A2 COMPOSITE NONLINEAR OPTICAL FILM, METHOD OF PRODUCING THE SAME AND APPLICATIONS OF THE SAME REVEO, INC. (US) 2002-01-31 WO claimed
WO-2002006890-A2 METHOD FOR PRODUCING NON-LINEAR OPTICAL ORGANIC CRYSTAL FILM REVEO, INC. (US) 2002-01-24 WO claimed
US-6303056-B1 Composite nonlinear optical film, method of producing the same and applications of the same REVEO, INC. 2001-10-16 US claimed
US-5981756-A ORGANIC NONLINEAR OPTICAL MATERIAL PROVIDED FOR DEVICES HAVING LARGE WAVELENGTH CONVERSION EFFICIENCY IN WAVELENGTH CONVERSION RELATING TO OPTICAL COMMUNICATIONS WAVELENGTH REGION, PARTICULARLY AT AROUND 1.55 MU M WAVELENGTH NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1999-11-09 US claimed
JP-9211512-A None JP disclosed
JP-10195053-A None JP disclosed
EP-1363423-B1 Data signal quality evaluation method and apparatus using high speed sampling NIPPON TELEGRAPH & TELEPHONE (JP) 2011-07-06 EP disclosed
US-5981756-A ORGANIC NONLINEAR OPTICAL MATERIAL PROVIDED FOR DEVICES HAVING LARGE WAVELENGTH CONVERSION EFFICIENCY IN WAVELENGTH CONVERSION RELATING TO OPTICAL COMMUNICATIONS WAVELENGTH REGION, PARTICULARLY AT AROUND 1.55 MU M WAVELENGTH NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1999-11-09 US disclosed
JP-H10195053-A DEUTERATED 2-ADAMANTYLAMINO-5-NITROPYRIDINE, ORGANIC NONLINEAR OPTICAL MATERIAL CONTAINING THE COMPOUND AND ITS PRODUCTION NIPPON TELEGR & TELEPH CORP <NTT> 1998-07-28 JP disclosed
JP-H09211512-A SECOND ORDER NONLINEAR OPTICAL ELEMENT NIPPON TELEGR & TELEPH CORP <NTT> 1997-08-15 JP disclosed