SCHEMBL6234527

SCHEMBL6234527

O=[N+]([O-])c1ccc(C23CC4CC(CC(C4)C2)C3)nc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
PGR P06401 1/20 0.44
ALDH1A1 P00352 6/20 0.43
MAPT P10636 4/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
LMNA P02545 2/20 0.41
CYP1A2 P05177 2/20 0.41
ALOX12 P18054 2/20 0.41
GAA P10253 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CYP2C9 P11712 2/20 0.39
HPGD P15428 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
SLC2A1 P11166 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18992722 0.78 NPC1 (0.69) NPC1RAB9APGRALDH1A1MAPT
SCHEMBL15071009 0.77 HSPB1 (0.59) NPC1RAB9APGRALDH1A1MAPT
SCHEMBL2152199 0.76 MEN1 (0.49) NPC1RAB9AALDH1A1MAPTMEN1
SCHEMBL27093614 0.73 CYP1A2 (0.49) NPC1RAB9AALDH1A1MAPTMEN1
SCHEMBL10346681 0.71 TSHR (0.47) NPC1RAB9AALDH1A1MAPTMEN1
SCHEMBL29186935 0.71 CYP1A2 (0.50) NPC1RAB9AALDH1A1MAPTMEN1
SCHEMBL15071010 0.71 RAB9A (0.59) NPC1RAB9APGRALDH1A1MAPT
SCHEMBL16054740 0.70 ALDH1A1 (0.47) NPC1RAB9AALDH1A1MAPTMEN1
SCHEMBL6234530 0.69 CYP2C9 (0.42) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL2152203 0.69 GAA (0.51) NPC1RAB9AALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1241458-B1 Optical sampling waveform measuring apparatus with high bandwidth ANRITSU CORP (JP) 2005-06-08 EP claimed
EP-1241458-B1 Optical sampling waveform measuring apparatus with high bandwidth ANRITSU CORP (JP) 2005-06-08 EP disclosed
US-6720548-B2 Optical sampling waveform measuring apparatus aiming at achieving wider band ANRITSU CORPORATION (JP) 2004-04-13 US disclosed
US-20020139924-A1 Optical sampling waveform measuring apparatus aiming at achieving wider band ANRITSU CORPORATION (JP) 2002-10-03 US disclosed
EP-1241458-A1 Optical sampling waveform measuring apparatus with high bandwidth ANRITSU CORPORATION (JP) 2002-09-18 EP disclosed