Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967024 | 0.77 | ALDH1A1 (0.59) | RAB9AMAPTGABBR2GABBR1LMNA | |
| SCHEMBL7966791 | 0.74 | RAB9A (0.61) | RAB9AMAPTALDH1A1TSHRNPC1 | |
| SCHEMBL2152199 | 0.73 | MEN1 (0.49) | RAB9AMAPTLMNAALDH1A1L3MBTL1 | |
| SCHEMBL23495205 | 0.71 | FDPS (0.40) | RAB9ALMNAALDH1A1L3MBTL1TSHR | |
| SCHEMBL7977522 | 0.71 | NPC1 (0.46) | RAB9AMAPTGABBR2GABBR1LMNA | |
| SCHEMBL7966600 | 0.71 | NOS3 (0.47) | RAB9AMAPTGABBR2GABBR1LMNA | |
| SCHEMBL21666863 | 0.68 | RAB9A (0.59) | RAB9AMAPTHDAC6ALDH1A1ADRA2A | |
| SCHEMBL19068266 | 0.68 | PDGFRB (0.49) | RAB9AMAPTGABBR2GABBR1LMNA | |
| SCHEMBL27304702 | 0.68 | MEN1 (0.43) | LMNAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL7994913 | 0.68 | L3MBTL1 (0.43) | RAB9AMAPTGABBR2GABBR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074778-A1 | (1-ADAMANTYLAMINO)PYRIDINES AND METHOD OF THEIR PREPARATION | FUNDACJA ROZWOJU DIAGNOSTYKI I TERAPII (PL) | 2001-10-11 | — | — | WO | claimed |
| WO-2001074778-A1 | (1-ADAMANTYLAMINO)PYRIDINES AND METHOD OF THEIR PREPARATION | FUNDACJA ROZWOJU DIAGNOSTYKI I TERAPII (PL) | 2001-10-11 | — | — | WO | disclosed |