SCHEMBL21523022

SCHEMBL21523022

CC(N)C(=O)NC(CNC(=O)C(C)(C(C)C)C(C)C)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GPR88 Q9GZN0 10/20 0.47
CTRB1 P17538 5/20 0.46
RIPK1 Q13546 1/20 0.42
METAP2 P50579 1/20 0.40
METAP1 P53582 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21523021 1.00 GPR88 (0.47) GPR88CTRB1RIPK1METAP2METAP1
Hydrochloric Acid SCHEMBL21523068 0.99 GPR88 (0.47) GPR88CTRB1RIPK1METAP2METAP1
Hydrochloric Acid SCHEMBL21523070 0.99 GPR88 (0.47) GPR88CTRB1RIPK1METAP2METAP1
SCHEMBL21523083 0.87 RIPK1 (0.46) RIPK1
SCHEMBL21523084 0.87 RIPK1 (0.46) RIPK1
SCHEMBL21523106 0.86 RIPK1 (0.41) GPR88RIPK1
SCHEMBL21523104 0.86 RIPK1 (0.41) GPR88RIPK1
SCHEMBL21523105 0.86 RIPK1 (0.41) GPR88RIPK1
SCHEMBL21531697 0.86 RIPK1 (0.41) GPR88RIPK1
SCHEMBL21531706 0.86 RIPK1 (0.41) GPR88RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190330141-A1 Compositions With A Cooling Effect THE PROCTER & GAMBLE COMPANY 2019-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190330141-A1 Compositions With A Cooling Effect CUTA, FABP4, EBP GPR88 733/4885CTRB1 1254/4885RIPK1 2148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.