Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10961574 | 0.84 | GABRA1 (0.46) | ATML3MBTL1ALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL19196801 | 0.76 | ALDH1A1 (0.43) | ATMMAPK1NPSR1MAPTALDH1A1 | |
| SCHEMBL8567630 | 0.75 | SLC6A4 (0.39) | ATMMAPK1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL27935806 | 0.75 | HTR2A (0.41) | PPARDPPARAMEN1KMT2AHTT | |
| SCHEMBL21449928 | 0.74 | CYP2D6 (0.41) | ATMMAPK1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19204117 | 0.74 | ALDH1A1 (0.44) | MAPK1NPSR1MAPTALDH1A1LMNA | |
| SCHEMBL11348933 | 0.73 | HTR2A (0.47) | PPARDPPARA | |
| SCHEMBL800010 | 0.73 | SMN1; SMN2 (0.49) | MAPK1NPSR1MAPTLMNASMN1; SMN2 | |
| SCHEMBL20207510 | 0.73 | CYP2D6 (0.40) | MAPK1MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5165521 | 0.73 | CYP2D6 (0.61) | MAPTALDH1A1SMN1; SMN2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10457655-B2 | Compounds and compositions for inhibition of FASN | FORMA THERAPEUTICS, INC. (US) | 2019-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10457655-B2 | Compounds and compositions for inhibition of FASN | FASN, FABP1, SCD | ATM 3716/4885CA1 2375/4885CA2 2965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.