SCHEMBL2152476

SCHEMBL2152476

N#CC1CCCCC1(C#N)N=NC1(C#N)CCCCC1C#N

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10361659 0.75 KDM4E (0.32) KDM4EMAPT
SCHEMBL2979879 0.71 KDM4E (0.34) KDM4EMAPT
SCHEMBL31307328 0.69
SCHEMBL3388937 0.69 KDM4E (0.31) KDM4EMAPT
SCHEMBL27963354 0.67 GAA (0.35) KDM4EMAPT
SCHEMBL19462668 0.65
SCHEMBL11121679 0.64 KDM4E (0.36) KDM4EMAPT
SCHEMBL9308229 0.64 KDM4E (0.36) KDM4EMAPT
SCHEMBL10457383 0.63 ALDH1A1 (0.41)
SCHEMBL5069504 0.63 ALDH1A1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070029279-A1 Wood treating formulation WOOD POLYMER TECHNOLOGIES ASA (NO) 2007-02-08 US claimed
EP-1253998-B1 WOOD IMPREGNATION WOOD POLYMER TECHNOLOGIES ASA (NO) 2004-03-24 EP claimed
US-20010033922-A1 Wood impregnation KEBONY ASA (NO) 2001-10-25 US claimed
US-9624225-B2 Quinolinyl modulators of RORγt JANSSEN PHARMACEUTICA NV (BE) 2017-04-18 US disclosed
US-20150111870-A1 QUINOLINYL MODULATORS OF RORyt JOHNSON & JOHNSON (US) 2015-04-23 US disclosed
EP-1658162-B1 WOOD TREATING FORMULATION KEBONY ASA (NO) 2011-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150111870-A1 QUINOLINYL MODULATORS OF RORyt RORC, RORA, RORB KDM4E 2003/4885MAPT 2335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.