SCHEMBL21526

SCHEMBL21526

CC(C)(C)C1(c2ccccc2)CC1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 4/20 0.45
GRIN2D O15399 1/20 0.45
GRIN3B O60391 1/20 0.45
CHRM2 P08172 1/20 0.45
CHRM1 P11229 1/20 0.45
GRIN1 Q05586 1/20 0.45
KCNH2 Q12809 1/20 0.45
GRIN2A Q12879 1/20 0.45
GRIN2B Q13224 1/20 0.45
GRIN2C Q14957 1/20 0.45
GRIN3A Q8TCU5 1/20 0.45
OPRK1 P41145 1/20 0.44
OPRL1 P41146 1/20 0.44
ALDH1A1 P00352 1/20 0.38
PNMT P11086 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
DRD4 P21917 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21524 1.00 OPRM1 (0.45) OPRM1GRIN2DGRIN3BCHRM2CHRM1
SCHEMBL16335846 0.89 SLC6A4 (0.44) GRIN2DGRIN3BGRIN1KCNH2GRIN2A
SCHEMBL25450725 0.85 ALDH1A1 (0.41) OPRM1GRIN2DGRIN3BCHRM2CHRM1
SCHEMBL24119450 0.83 OPRM1 (0.52) OPRM1GRIN2DGRIN3BCHRM2CHRM1
SCHEMBL2840979 0.81 OPRM1 (0.47) OPRM1GRIN2DGRIN3BCHRM2CHRM1
SCHEMBL24119452 0.78 OPRM1 (0.46) OPRM1GRIN2DGRIN3BCHRM2CHRM1
SCHEMBL23511277 0.78 OPRM1 (0.37) OPRM1GRIN2DGRIN3BCHRM2CHRM1
SCHEMBL18022527 0.76 SLC6A3 (0.39) MAOAMAOB
SCHEMBL13028798 0.76 KIF11 (0.35)
SCHEMBL10244935 0.76 SLC6A4 (0.40) OPRM1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3253561-B1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2019-05-08 EP claimed
US-10105908-B2 Process for producing modified olefin polymer in an extruder BOREALIS AG (AT) 2018-10-23 US claimed
US-20170361543-A1 Process for Producing Modified Olefin Polymer in an Extruder BOREALIS AG (AT) 2017-12-21 US claimed
WO-2016124617-A1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2016-08-11 WO claimed
EP-4086299-B1 THERMALLY TREATED BIAXIALLY ORIENTED POLYPROPYLENE FILM BOREALIS AG (AT) 2024-07-03 EP disclosed
EP-4393969-A1 PROPYLENE COMPOSITION Borealis AG (AT) 2024-07-03 EP disclosed
EP-3898237-B1 BIAXIALLY ORIENTED POLYPROPYLENE FILM WITH IMPROVED SURFACE PROPERTIES BOREALIS AG (AT) 2024-04-17 EP disclosed
EP-3487927-B1 STIFF PROPYLENE COMPOSITION WITH GOOD DIMENSIONAL STABILITY AND EXCELLENT SURFACE APPEARANCE BOREALIS AG (AT) 2024-03-27 EP disclosed
EP-3532540-B1 HIGH FLOW HETEROPHASIC POLYPROPYLENE COPOLYMERS WITH IMPROVED MECHANICAL AND OPTICAL PROPERTIES BOREALIS AG (AT) 2024-03-13 EP disclosed
US-20230405969-A1 MULTILAYER SHEET COMPRISING A FOAMED LAYER SUITABLE FOR FOOD PACKAGING BOREALIS AG (AT) 2023-12-21 US disclosed
CN-117203269-A Biaxially oriented polypropylene film after heat treatment 博里利斯股份公司 2023-12-08 CN disclosed
US-20230227620-A1 HMS PP FOAM SHEET WITH GOOD COMPRESSIVE STRENGTH AND RECOVERABILITY BOREALIS AG (AT) 2023-07-20 US disclosed
US-20010016628-A1 Modified with less than 5% by weight of monofunctional, difunctional and polyfunctional monomers; improved melt processability; sheets, films, panels, coatings, pipes, hollow objects and foams BOREALIS GMBH (AU) 2001-08-23 US disclosed
US-6242525-B1 PROPYLENE HOMOPOLYMERS AND/OR COPOLYMERS WITH ELASTOMERS OF READILY VOLATILE DIENES IN THE PRESENCE OF THERMALLY DECOMPOSING FREE RADICAL-FORMING AGENTS; THERMOPLASTIC ELASTOMERS WITH A FINE DISPERSION DISTRIBUTION BOREALIS GMBH (AT) 2001-06-05 US disclosed
US-6225366-B1 USED IN PACKAGING SECTOR, MOTOR VEHICLE PARTS, SPORTS AND LEISURE EQUIPMENT, INDUSTRIAL APPLICATIONS, AS WELL AS APPLICATIONS IN THE BUILDING MATERIAL BOREALIS AG (AT) 2001-05-01 US disclosed
US-6218011-B1 Polyolefin fibers and polyolefin yarns and textile fabrics produced therefrom BOREALIS GMBH (AT) 2001-04-17 US disclosed
US-6204348-B1 REACTING A POLYPROPYLENE WITH ETHYLENICALLY UNSATURATED MONOMER BOREALIS GMBH (AT) 2001-03-20 US disclosed
US-6136926-A CURING WITH ETHYLENICALLY UNSATURATED ORGANOSILANE COMPOUND; HEATING BELOW SOFTENING POINT BOREALIS GMBH (AT) 2000-10-24 US disclosed
US-5962594-A Segmented polyolefins BOREALIS AG (AT) 1999-10-05 US disclosed
US-5929127-A Fine-celled polyolefin foam materials BOREALIS AG (AT) 1999-07-27 US disclosed