SCHEMBL21526039

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20356565	0.89	NPSR1 (0.40)	HTTHPGDNPSR1P2RX7LMNA
	SCHEMBL20356667	0.89	SMN1; SMN2 (0.54)	HTTSMN1; SMN2P2RX7NR4A2PTGDR
	SCHEMBL20356578	0.88	SMN1; SMN2 (0.44)	HTTSMN1; SMN2P2RX7NR4A2KDM4E
	SCHEMBL20356569	0.88	ALDH1A1 (0.49)	HTTHPGDNPSR1P2RX7LMNA
	SCHEMBL20356563	0.85	MBOAT4 (0.40)	HTTHPGDLMNAALDH1A1HSD17B10
	SCHEMBL21525996	0.85	SMN1; SMN2 (0.48)	HTTSMN1; SMN2HPGDP2RX7LMNA
	SCHEMBL21526112	0.85	SMN1; SMN2 (0.41)	HTTSMN1; SMN2NR4A2PTGDRKDM4C
	SCHEMBL21526053	0.85	SMN1; SMN2 (0.50)	HTTSMN1; SMN2P2RX7NR4A2PTGDR
	SCHEMBL21526102	0.84	SMN1; SMN2 (0.47)	HTTSMN1; SMN2HPGDP2RX7LMNA
	SCHEMBL21548933	0.83	SMN1; SMN2 (0.61)	HTTSMN1; SMN2P2RX7LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.