SCHEMBL21528806

SCHEMBL21528806

O=C(O)N[C@H](Cc1ccc(-c2ccc(C(F)(F)F)cc2)cc1)C(=O)N1CCCCC1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ FPR2 P25090 8/20 0.48
▸ MTTP P55157 3/20 0.48
▸ FPR1 P21462 4/20 0.47
▸ MEN1 O00255 1/20 0.46
▸ HPGD P15428 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ CYP3A4 P08684 1/20 0.44
▸ CALCRL Q16602 1/20 0.44
▸ P2RX7 Q99572 1/20 0.43
▸ KDM4E B2RXH2 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ MMP1 P03956 1/20 0.41
▸ MMP3 P08254 1/20 0.41
▸ KLRK1 P26718 1/20 0.41
▸ MICA Q29983 1/20 0.41
▸ RAET1L Q5VY80 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21528807 1.00 FPR2 (0.48) FPR2MTTPFPR1MEN1HPGD
SCHEMBL21529031 0.88 MTTP (0.49) MTTPTSHRP2RX7MMP1MMP3
SCHEMBL21529162 0.88 MTTP (0.49) MTTPTSHRP2RX7MMP1MMP3
SCHEMBL16289262 0.81 FPR2 (0.53) FPR2FPR1MEN1HPGDTSHR
SCHEMBL16289260 0.81 FPR2 (0.53) FPR2FPR1MEN1HPGDTSHR
SCHEMBL4205338 0.80 FPR2 (0.52) FPR2FPR1MEN1TSHRKMT2A
SCHEMBL5552607 0.80 FPR2 (0.52) FPR2FPR1MEN1TSHRKMT2A
SCHEMBL4214360 0.80 FPR2 (0.52) FPR2FPR1MEN1TSHRKMT2A
Hydrochloric Acid SCHEMBL4725522 0.79 FPR2 (0.51) FPR2FPR1MEN1KMT2AKDM4E
SCHEMBL13791833 0.77 ECE1 (0.42) FPR2MTTPFPR1CYP3A4P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11384060-B2 Amide compounds and use thereof ALPHALA CO., LTD. (TW) 2022-07-12 — — US disclosed
US-20190337915-A1 AMIDE COMPOUNDS AND USE THEREOF ALPHALA CO., LTD. (TW) 2019-11-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190337915-A1 AMIDE COMPOUNDS AND USE THEREOF GLP1R, IAPP, GPR119 FPR2 1878/4885MTTP 419/4885FPR1 685/4885
US-11384060-B2 Amide compounds and use thereof GLP1R, IAPP, GPR119 FPR2 1878/4885MTTP 419/4885FPR1 685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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