SCHEMBL2152977

SCHEMBL2152977

CCCCNC(=N)NC#N

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 4/20 0.38
ACHE P22303 8/20 0.35
MMP2 P08253 2/20 0.35
MGLL Q99685 1/20 0.35
HTT P42858 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.32
MMP1 P03956 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2152670 0.94 EPHX1 (0.42) EPHX1MGLLTSHR
SCHEMBL1937986 0.92 EPHX1 (0.45) EPHX1MGLL
SCHEMBL1937316 0.92 EPHX1 (0.45) EPHX1MGLL
SCHEMBL11125409 0.92 EPHX1 (0.45) EPHX1MGLL
SCHEMBL11726259 0.92 EPHX1 (0.45) EPHX1MGLL
SCHEMBL12669343 0.92 EPHX1 (0.45) EPHX1MGLL
SCHEMBL1937657 0.92 EPHX1 (0.45) EPHX1MGLL
SCHEMBL11810751 0.92 EPHX1 (0.45) EPHX1MGLL
SCHEMBL2152762 0.92 EPHX1 (0.45) EPHX1MGLL
SCHEMBL918587 0.92 EPHX1 (0.45) EPHX1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250235390-A1 Composition and Process for Treating a Disorder in the Oral Cavity of a Mammal SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2025-07-24 US disclosed
EP-3534867-B1 MEDICAL COMPOSITION CONTAINING GUANIDINYL-CONTAINING POLYMER(S) AND CARRAGEENANE(S) SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-06-04 EP disclosed
EP-3534866-B1 METHOD OF DENTAL RETRACTION WITH COMPOSITION WITH GUANIDINYL-CONTAINING POLYMER SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-05-28 EP disclosed
US-12295369-B2 Articles containing a crosslinked guanidinyl-containing polymer and uses thereof SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-05-13 US disclosed
US-20250082440-A1 Composition for Isolating Tissue SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2025-03-13 US disclosed
EP-4419062-A1 COMPOSITION AND PROCESS FOR TREATING A DISORDER IN THE ORAL CAVITY OF A MAMMAL Solventum Intellectual Properties Company (US) 2024-08-28 EP disclosed
CN-114173560-B Articles comprising crosslinked guanidine-containing polymers and uses thereof 舒万诺知识产权公司 2024-07-09 CN disclosed
EP-4380494-A1 COMPOSITION FOR ISOLATING TISSUE Solventum Intellectual Properties Company (US) 2024-06-12 EP disclosed
US-20240024205-A1 DENTAL RETRACTION COMPOSITION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-01-25 US disclosed
US-11827864-B2 Wipe with a guanidinyl-containing polymer 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-11-28 US disclosed
EP-1913070-B1 STABILISER COMPOSITIONS BASED ON NITROGEN COMPOUNDS FOR STABILISING HALOGENATED POLYMERS BAERLOCHER GMBH (DE) 2011-07-06 EP disclosed
US-20090048374-A1 STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE BAERLOCHER GMBH (DE) 2009-02-19 US disclosed
EP-1996649-A1 STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE Baerlocher GmbH (DE) 2008-12-03 EP disclosed
EP-1913067-A1 STABILIZER COMPOSITIONS BASED ON GUANIDINE OR MELAMINE COMPOUNDS TO STABILIZE HALOGEN-CONTAINING POLYMERS Baerlocher GmbH (DE) 2008-04-23 EP disclosed
EP-1913070-A2 STABILISER COMPOSITIONS BASED ON NITROGEN COMPOUNDS FOR STABILISING HALOGENATED POLYMERS Baerlocher GmbH (DE) 2008-04-23 EP disclosed
WO-2007104379-A1 STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE BAERLOCHER GMBH (DE) 2007-09-20 WO disclosed
WO-2007019999-A1 STABILIZER COMPOSITIONS BASED ON GUANIDINE OR MELAMINE COMPOUNDS TO STABILIZE HALOGEN-CONTAINING POLYMERS BAERLOCHER GMBH (DE) 2007-02-22 WO disclosed
WO-2007020000-A2 STABILISER COMPOSITIONS BASED ON NITROGEN COMPOUNDS FOR STABILISING HALOGENATED POLYMERS BAERLOCHER GMBH (DE) 2007-02-22 WO disclosed
US-4670592-A BACTERICIDES, FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-06-02 US disclosed
EP-0125092-A1 Bisbiguanide compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12295369-B2 Articles containing a crosslinked guanidinyl-containing polymer and uses thereof C5, YTHDC1, PRMT1 EPHX1 1306/4885ACHE 2078/4885MMP2 2019/4885
US-20240024205-A1 DENTAL RETRACTION COMPOSITION GK, GANC, JMJD1C EPHX1 4493/4885ACHE 1647/4885MMP2 1063/4885
US-20250235390-A1 Composition and Process for Treating a Disorder in the Oral Cavity of a Mammal GSDMD, PIGS, GANC EPHX1 961/4885ACHE 826/4885MMP2 160/4885
US-11827864-B2 Wipe with a guanidinyl-containing polymer GNPDA1, GDA, PGLS EPHX1 2349/4885ACHE 2050/4885MMP2 1123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.