SCHEMBL2153003

SCHEMBL2153003

CCC1=CC(=O)N(n2cccc2)C1=O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.39
XPO1 O14980 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL712319 0.76 MGLL (0.38) XPO1
SCHEMBL14314260 0.69 MGLL (0.36) XPO1
SCHEMBL11297655 0.68 XPO1 (0.32) XPO1
SCHEMBL1172858 0.67 XPO1 (0.33) XPO1
Bicarbonate SCHEMBL3183815 0.65 ALDH1A1 (0.40) POLBXPO1
SCHEMBL2284447 0.62 POLB (0.48) POLB
SCHEMBL16156025 0.61 MGLL (0.32) XPO1
SCHEMBL787534 0.60 XPO1 (0.30) XPO1
SCHEMBL2152999 0.60 MGLL (0.32) XPO1
SCHEMBL9276702 0.58 MGLL (0.52) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170121761-A1 ELECTRICAL DETECTION OF A DNA OR RNA TARGET IN A SAMPLE TECHNION RES & DEV FOUNDATION (IL) 2017-05-04 US disclosed
US-20120309106-A1 DETECTION OF A TARGET IN A SAMPLE TECHNION RESEARCH AND DEVELOPMENT FOUNDATION, LTD. (IL) 2012-12-06 US disclosed
EP-1075656-B1 DETECTION OF A TARGET IN A SAMPLE TECHNION RES & DEV FOUNDATION (IL) 2011-07-06 EP disclosed
US-20030203394-A1 Detection of a target in a sample EICHEN YOAV (IL) 2003-10-30 US disclosed
EP-1075656-A1 DETECTION OF A TARGET IN A SAMPLE Technion Research & Development Foundation Limited (IL) 2001-02-14 EP disclosed
WO-1999057550-A1 DETECTION OF A TARGET IN A SAMPLE TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) 1999-11-11 WO disclosed